Khalid El-Jack, Fawaz Naeem, Jenelle Safadi, Dario Marangoni, Alexander M Solomon, Franz Fogt, Grant T Liu, Madhura A Tamhankar
{"title":"Unusual systemic conditions in a patient with giant cell arteritis.","authors":"Khalid El-Jack, Fawaz Naeem, Jenelle Safadi, Dario Marangoni, Alexander M Solomon, Franz Fogt, Grant T Liu, Madhura A Tamhankar","doi":"10.1093/mrcr/rxaf014","DOIUrl":null,"url":null,"abstract":"<p><p>Giant cell arteritis is a systemic vasculitis that causes inflammation in medium- and large-sized blood vessels. The condition can lead to irreversible blindness if not recognised and treated promptly with high-dose steroids. Clinical manifestations typically include headache, jaw pain, fever, and fatigue. However, unusual manifestations of the disease have been reported, including pulmonary nodules, uveitis, pericarditis, and stroke. We report a case of biopsy-confirmed giant cell arteritis in a patient found to have renal cell carcinoma, exhibiting these unusual manifestations simultaneously. This case report demonstrates the atypical presentation that giant cell arteritis may have and the importance of having a high clinical suspicion for the condition.</p>","PeriodicalId":94146,"journal":{"name":"Modern rheumatology case reports","volume":" ","pages":""},"PeriodicalIF":0.9000,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Modern rheumatology case reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/mrcr/rxaf014","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"RHEUMATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Giant cell arteritis is a systemic vasculitis that causes inflammation in medium- and large-sized blood vessels. The condition can lead to irreversible blindness if not recognised and treated promptly with high-dose steroids. Clinical manifestations typically include headache, jaw pain, fever, and fatigue. However, unusual manifestations of the disease have been reported, including pulmonary nodules, uveitis, pericarditis, and stroke. We report a case of biopsy-confirmed giant cell arteritis in a patient found to have renal cell carcinoma, exhibiting these unusual manifestations simultaneously. This case report demonstrates the atypical presentation that giant cell arteritis may have and the importance of having a high clinical suspicion for the condition.