Exploring the utility of near-infrared spectroscopy in liver transplantation: insights and challenges.

Clinical transplantation and research Pub Date : 2025-06-30 Epub Date: 2025-03-14 DOI:10.4285/ctr.24.0067

Ravshan Ibadov, Konstantin Semash, Mirshavkat Akbarov, Timur Dzhanbekov, Oybek Omonov, Azimjon Usmonov, Sardor Ibragimov

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Abstract

Maintaining adequate tissue perfusion and oxygen delivery to the transplanted liver is critical for positive patient outcomes. Near-infrared spectroscopy (NIRS) has emerged as a promising tool for evaluating graft function in liver transplantation, particularly in assessing tissue perfusion. This review consolidates current knowledge regarding the application of NIRS in liver transplantation, highlighting its potential for noninvasive, continuous monitoring of liver perfusion and early detection of hemodynamic disturbances. Initial studies demonstrate the sensitivity of NIRS in evaluating liver oxygenation, with significant correlations observed between NIRS readings and biochemical markers of liver function. However, the effectiveness of NIRS can be influenced by factors such as subcutaneous fat thickness and patient positioning. Recent advancements also suggest that NIRS may assist in predicting graft fibrosis and other longterm complications. More extensive studies are required to establish standardized protocols and validate the clinical utility of NIRS in liver transplantation.

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探索近红外光谱在肝移植中的应用：见解和挑战。

维持足够的组织灌注和氧气输送到移植肝脏是积极的患者预后的关键。近红外光谱（NIRS）已成为评估肝移植中移植物功能的一种有前途的工具，特别是在评估组织灌注方面。这篇综述整合了目前关于近红外光谱在肝移植中的应用的知识，强调了其在无创、连续监测肝灌注和早期发现血流动力学紊乱方面的潜力。初步研究表明，近红外光谱在评估肝氧合方面具有敏感性，近红外光谱读数与肝功能生化指标之间存在显著相关性。然而，近红外光谱的有效性可能受到皮下脂肪厚度和患者体位等因素的影响。最近的进展也表明，近红外光谱可能有助于预测移植物纤维化和其他长期并发症。需要更广泛的研究来建立标准化的方案，并验证近红外光谱在肝移植中的临床应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Clinical transplantation and research

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