Burden of Atrial Fibrillation and Atrial Flutter From 1990 to 2021 in China: Global Burden of Disease Study 2021 Update.

IF 1.7 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Pace-Pacing and Clinical Electrophysiology Pub Date : 2025-04-01 Epub Date: 2025-03-13 DOI:10.1111/pace.15175

Xiangyi Kong, Mingxiao Li, Liu He, Yiwei Lai, Jue Wang, Sitong Li, Xiaodong Peng, Manlin Zhao, Qifan Li, Zixu Zhao, Le Zhou, Zejun Yang, Ting Shen, Meiqi Zhao, Zhixian Wang, Enze Li, Yize Zhao, Wenyu Wang, Shijun Xia, Chao Jiang, Xueyuan Guo, Ning Zhou, Xin Du, Caihua Sang, Jianzeng Dong, Changsheng Ma

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引用次数: 0

Abstract

Background: Atrial fibrillation (AF) and atrial flutter (AFL) represent increasingly significant health burden globally. We aimed to systematically evaluate the status and trends of AF/AFL burden and attributable risk factors in China.

Methods: We assessed the burden of AF/AFL measured as prevalence, incidence, mortality, and disability-adjusted life years (DALYs), by sex and age groups in China based on the Global Burden of Diseases Study (GBD) 2021 project.

Results: In China, there were 10,775.72 thousand AF/AFL prevalent cases, 916.18 thousand AF/AFL incident cases, and 64.73 thousand AF/AFL mortality cases, contributing to 1653.12 thousand DALYs due to AF/AFL in 2021. Trend analysis indicated that the AAPC of number and crude rates of prevalence, incidence, mortality, and DALYs all escalated from 1990 to 2021. The current AF/AFL burden and temporal trend between 1990 and 2021 displayed heterogeneity based on sex and age groups. The spectrum for risk factors attributed for DALYs due to AF/AFL presented sex- and age-specific manifestation. High systolic blood pressure served as the emerging leading contributor to DALYs due to AF/AFL in China.

Conclusion: A significant increase in the burden of AF/AFL underscores the enduring public health burden of AF/AFL in China, marked by profound sex and age-related variations. There is a pressing imperative to adopt tailored strategies to attenuate increasing burden of AF/AFL and combat alongside high complication burden due to AF/AFL in China.

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1990 年至 2021 年中国心房颤动和心房扑动的负担：全球疾病负担研究2021年更新版》。

背景：房颤（AF）和心房扑动（AFL）是全球范围内日益严重的健康负担。我们旨在系统地评估中国AF/AFL负担的现状和趋势以及归因危险因素。方法：基于全球疾病负担研究（GBD） 2021项目，我们评估了中国按性别和年龄组衡量的AF/AFL负担，包括患病率、发病率、死亡率和残疾调整生命年（DALYs）。结果：中国AF/AFL流行病例10775.72万例，AF/AFL发病病例916.18万例，AF/AFL死亡病例64.73万例，2021年AF/AFL的DALYs为1653.12万。趋势分析表明，从1990年到2021年，患病率、发病率、死亡率和DALYs的数量和粗比率的AAPC均呈上升趋势。目前AF/AFL负担和1990年至2021年的时间趋势显示出性别和年龄组的异质性。AF/AFL导致DALYs的危险因素谱呈现出性别和年龄特异性表现。在中国，高收缩压是AF/AFL导致的DALYs的主要因素。结论：AF/AFL负担的显著增加强调了AF/AFL在中国持续存在的公共卫生负担，其特征是与性别和年龄相关的深刻差异。在中国，迫切需要采取量身定制的策略来减轻AF/AFL日益增加的负担，并与AF/AFL造成的高并发症负担作斗争。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pace-Pacing and Clinical Electrophysiology 医学-工程：生物医学

CiteScore

2.70

自引率

5.60%

发文量

209

审稿时长

2-4 weeks

期刊介绍： Pacing and Clinical Electrophysiology (PACE) is the foremost peer-reviewed journal in the field of pacing and implantable cardioversion defibrillation, publishing over 50% of all English language articles in its field, featuring original, review, and didactic papers, and case reports related to daily practice. Articles also include editorials, book reviews, Musings on humane topics relevant to medical practice, electrophysiology (EP) rounds, device rounds, and information concerning the quality of devices used in the practice of the specialty.