Investigation of the tissue equivalence of typical 3D-printing materials for application in internal dosimetry using monte carlo simulations.

IF 2.4 4区医学 Q3 ENGINEERING, BIOMEDICAL

Physical and Engineering Sciences in Medicine Pub Date : 2025-03-13 DOI:10.1007/s13246-025-01532-2

Ayse Karadeniz-Yildirim, Handan Tanyildizi-Kokkulunk

引用次数: 0

Abstract

This study evaluates the dosimetric accuracy of PLA and ABS 3D-printed phantoms compared to real tissues using Monte Carlo simulations in radionuclide therapy.

Materials and methods: A phantom representing average liver and lung volumes, with a 10 mm tumor mimic in the liver, was simulated for radioembolization using 1 mCi Tc-99 m and 1 mCi Y-90. The dose distribution (DD) was compared across PLA, ABS, and real organ densities.

Results: For Tc-99 m, PLA showed a + 5.6% DD difference in the liver, and ABS showed - 35.3% and - 40.9% differences in the lungs. For Y-90, PLA had a + 1.7% DD difference in the liver, while ABS showed - 34.2% and - 34.9% differences in the lungs.

Conclusion: In MC simulation, PLA is suitable for representing high-density tissues, while ABS is appropriate for simulating moderately low-density tissues.

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利用蒙特卡罗模拟研究典型3d打印材料在内剂量学中的组织等效性。

本研究评估PLA和ABS 3d打印的模型与真实组织在放射性核素治疗中使用蒙特卡罗模拟的剂量准确性。材料和方法：模拟一个代表肝脏和肺平均体积的假体，在肝脏中有一个10毫米的肿瘤模拟物，用1 mCi Tc-99 m和1 mCi Y-90模拟放射栓塞。剂量分布（DD）在PLA、ABS和真实器官密度之间进行比较。结果：对于tc - 99m， PLA在肝脏的DD差异为+ 5.6%，ABS在肺部的DD差异为- 35.3%和- 40.9%。对于Y-90， PLA在肝脏中有+ 1.7%的DD差异，而ABS在肺中有- 34.2%和- 34.9%的差异。结论：在MC模拟中，PLA适用于模拟高密度组织，ABS适用于模拟中低密度组织。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Physical and Engineering Sciences in Medicine Multiple-

CiteScore

8.40

自引率

4.50%

发文量

110