A Dual-Emissive DNA-Templated Silver Nanocluster with Near-Infrared I and II Emission

IF 8 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

Advanced Optical Materials Pub Date : 2025-01-16 DOI:10.1002/adom.202402752

Anna Gonzàlez-Rosell, Vanessa Rück, Mikkel B. Liisberg, Cecilia Cerretani, Villads R. M. Nielsen, Tom Vosch, Stacy M. Copp

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Abstract

DNA-stabilized silver nanoclusters (DNA-Ag_N) are atomically precise and sequence-tuned nanomaterials with potential applications for deep tissue biomedical imaging. Here, a dual-emissive DNA-Ag_N is presented with fluorescence in the first near-infrared (NIR-I) spectral window and microsecond-lived photoluminescence in the second near-infrared (NIR-II) spectral window. High-resolution electrospray ionization mass spectrometry showed that the emitter has the molecular formula (DNA)₂[Ag₁₇]¹¹⁺. The crystallization of (DNA)₂[Ag₁₇]¹¹⁺ was unsuccessful, which prevented the use of X-ray diffraction to determine its structure. However, sequence variations of the templating DNA oligomer provided insights into nucleobases that are critical for stabilizing the Ag₁₇¹¹⁺. Moreover, addition of an adenosine or thymidine at the 5′-end of the stabilizing DNA strand maintained the composition and photophysical properties of the (DNA)₂[Ag₁₇]¹¹⁺, suggesting a potential site for conjugation with biomolecules to enable targeted labeling in future bioimaging applications.

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来源期刊

Advanced Optical Materials MATERIALS SCIENCE, MULTIDISCIPLINARY-OPTICS

CiteScore

13.70

自引率

6.70%

发文量

883

审稿时长

1.5 months

期刊介绍： Advanced Optical Materials, part of the esteemed Advanced portfolio, is a unique materials science journal concentrating on all facets of light-matter interactions. For over a decade, it has been the preferred optical materials journal for significant discoveries in photonics, plasmonics, metamaterials, and more. The Advanced portfolio from Wiley is a collection of globally respected, high-impact journals that disseminate the best science from established and emerging researchers, aiding them in fulfilling their mission and amplifying the reach of their scientific discoveries.