Palladium-Catalyzed Selective B(3)-Esterification of o-Carboranes with CO and Alcohols

IF 5 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Letters Pub Date : 2025-03-03 DOI:10.1021/acs.orglett.5c0030810.1021/acs.orglett.5c00308

Shuai Zhu, Yizhen Liu and Zuowei Xie*,

引用次数: 0

Abstract

Selective functionalization of o-carboranes has received tremendous attention, specifically in the regioselective modification of the ten chemically similar BH vertices within o-carborane cage. We disclose herein a strategy for palladium-catalyzed esterification of the B(3)–H bond in o-carboranes using tungsten hexacarbonyl as a carbon monoxide source. The corresponding functionalized o-carboranes were prepared in moderate to very good yields with excellent regioselectivity.

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钯催化邻碳硼烷与CO和醇的选择性B(3)-酯化反应

邻碳硼烷的选择性功能化受到了广泛的关注，特别是对邻碳硼烷笼内10个化学性质相似的BH顶点的区域选择性修饰。我们在此公开了一种使用六羰基钨作为一氧化碳源，钯催化邻碳硼烷中B(3) -H键酯化的策略。相应的功能化邻碳硼烷具有优异的区域选择性，产率中至极好。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Organic Letters 化学-有机化学

CiteScore

9.30

自引率

11.50%

发文量

1607

审稿时长

1.5 months

期刊介绍： Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.