Risk factors for oral mucosal pressure injury associated with endotracheal tubes in intensive care unit patients: A single-centre longitudinal study with brief follow-up.

IF 3 3区 医学 Q1 NURSING
Ecem Ozdemir, Oznur Kavakli
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引用次数: 0

Abstract

Background: In intensive care units (ICUs), endotracheal tubes (ETTs) cause injury to the oral mucosa through friction and pressure. The incidence and risk factors of oral mucosal pressure injuries (PIs) have gained increasing attention in recent years.

Aim: The study aimed to identify risk factors for oral mucosal PIs associated with ETTs.

Study design: This was a single-centre brief follow-up longitudinal study conducted from January to May 2022. It recruited 250 patients without oral mucosal PIs who received mechanical ventilation support via ETT and were hospitalized in the ICU of a teaching and research hospital in Turkey. Receiver operating characteristic (ROC) analysis was performed to estimate the onset time of oral mucosal PI using the ETT repositioning time as an independent variable.

Results: Oral mucosal PIs associated with ETT developed in 41.6% of patients. Of the 250 endotracheally intubated patients, the mean Acute Physiology and Chronic Health Evaluation (APACHE-II) score was 27.5 (min/max: 18/42), the mean length of stay (LOS) in the ICU was 24 days (min/max: 13/80). The median body mass index (BMI) of patients with oral mucosal PIs was (24.59 [IQR = 3.81] kg/m2), significantly lower than the median BMI of patients without oral mucosal PIs (26.62 [IQR = 5.93] kg/m2) (Z = 4.200; p < .001). The earliest onset of oral mucosal PIs was noted at 16 h after the start of follow-up, and the latest was 208 h after the start of follow-up, with a median of 160 (IQR = 48) h (approximately 6.7 days). Patients whose ETT was repositioned after 10.5 h had a higher risk of developing oral mucosal PIs (OR = 3.77; 95% CI: 2.65-5.37; p < .001). The decision tree (CHAID) method was applied to determine the time required to reposition the ETT to prevent oral mucosal PIs. The decision tree correctly classified the occurrence of oral mucosal PIs by 60.6% and the non-occurrence of oral mucosal PIs by 97.9%. Patients with parenteral nutrition and a low frequency of ETT repositioning time had a higher risk of oral mucosal PIs (p < .001).

Conclusions: Parenteral nutrition support and ETT repositioning timing were the primary risk factors for developing oral mucosal PIs. Close monitoring of endotracheally intubated patients receiving parenteral nutrition is essential, with particular attention to forming oral mucosal PIs. Additionally, repositioning the ETT at intervals of no more than 8 h may help reduce the risk of oral mucosal PI development.

Relevance to clinical practice: As ICU patients are particularly vulnerable to mucosal membrane PIs, recognizing the associated risk factors is crucial for early detection and prevention. This study highlights the specific risk factors for oral mucosal PIs, equipping nurses with the knowledge to develop targeted interventions to prevent these injuries.

重症监护病房患者与气管插管相关的口腔黏膜压力损伤的危险因素:一项简短随访的单中心纵向研究。
背景:在重症监护病房(icu),气管内管(ets)通过摩擦和压力对口腔黏膜造成损伤。近年来,口腔粘膜压力损伤的发生率和危险因素越来越受到人们的关注。目的:本研究旨在确定与e.t相关的口腔黏膜PIs的危险因素。研究设计:这是一项单中心短期随访纵向研究,于2022年1月至5月进行。该研究招募了250例无口腔黏膜不良反应的患者,这些患者通过ETT接受机械通气支持,并在土耳其一家教学和研究医院的ICU住院。以ETT重新定位时间为自变量,进行受试者工作特征(ROC)分析,估计口腔黏膜PI的发病时间。结果:41.6%的患者发生了与ETT相关的口腔黏膜PIs。250例经气管插管患者急性生理和慢性健康评估(APACHE-II)平均评分为27.5 (min/max: 18/42),平均在ICU住院时间(LOS)为24天(min/max: 13/80)。口腔黏膜不良反应患者的中位体重指数(BMI)为(24.59 [IQR = 3.81] kg/m2),显著低于无口腔黏膜不良反应患者的中位体重指数(26.62 [IQR = 5.93] kg/m2) (Z = 4.200;结论:肠外营养支持和ETT重新定位时机是发生口腔黏膜pi的主要危险因素。密切监测气管内插管接受肠外营养的患者是必要的,特别注意形成口腔黏膜pi。此外,每隔不超过8小时重新定位ETT可能有助于降低口腔黏膜PI发展的风险。与临床实践的相关性:由于ICU患者特别容易发生粘膜pi,认识相关的危险因素对于早期发现和预防至关重要。本研究强调了口腔粘膜PIs的具体危险因素,为护士提供了制定有针对性的干预措施以预防这些伤害的知识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.00
自引率
13.30%
发文量
109
审稿时长
>12 weeks
期刊介绍: Nursing in Critical Care is an international peer-reviewed journal covering any aspect of critical care nursing practice, research, education or management. Critical care nursing is defined as the whole spectrum of skills, knowledge and attitudes utilised by practitioners in any setting where adults or children, and their families, are experiencing acute and critical illness. Such settings encompass general and specialist hospitals, and the community. Nursing in Critical Care covers the diverse specialities of critical care nursing including surgery, medicine, cardiac, renal, neurosciences, haematology, obstetrics, accident and emergency, neonatal nursing and paediatrics. Papers published in the journal normally fall into one of the following categories: -research reports -literature reviews -developments in practice, education or management -reflections on practice
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