Revealing the Future of Pharmacovigilance in Precision Pharmaceutical Monitoring.

IF 1.1 Q4 PHARMACOLOGY & PHARMACY
Vishnu Mittal, Anjali Sharma
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引用次数: 0

Abstract

The growing popularity of personalized medicine presents new hazards and difficulties for pharmacovigilance. This implies that it needs to modify its current approach. This research examines how drug safety monitoring for certain medications evolves over time. We briefly discuss the connection between meticulous pharmacovigilance procedures and adaptable treatment approaches. We describe how pharmacogenetics may be used to make drugs safer and how genetic testing may be used to forecast a drug's potential side effects. With an emphasis on post-marketing monitoring in phase IV, we address shortcomings of research on pre-marketing and the need for a comprehensive strategy for medication safety. The significance of pharmacogenetics in reducing risk before exposure and the need to reconsider pharmacoepidemiological techniques for monitoring outcomes after exposure are discussed in the study. We emphasize the significance of including genetic patient-specific profiles in publications related to tailored therapy and the use of state-of-the-art computer techniques for data processing. We also discuss privacy, ethical, and data security issues that arise with precision medicine, emphasizing the consequences for patient consent and data management.

揭示精准药物监测中药物警戒的未来。
个性化医疗的日益普及给药物警戒带来了新的危害和困难。这意味着它需要修改其当前的方法。本研究考察了某些药物的药物安全监测如何随着时间的推移而发展。我们简要讨论细致的药物警戒程序和适应性治疗方法之间的联系。我们描述了如何使用药物遗传学使药物更安全,以及如何使用基因检测来预测药物的潜在副作用。重点是第四阶段的上市后监测,我们解决了上市前研究的缺点和药物安全综合战略的需要。研究中讨论了药物遗传学在降低暴露前风险方面的重要性,以及重新考虑暴露后监测结果的药物流行病学技术的必要性。我们强调在与定制治疗和使用最先进的计算机技术进行数据处理相关的出版物中包括遗传患者特定概况的重要性。我们还讨论了与精准医疗相关的隐私、伦理和数据安全问题,强调了患者同意和数据管理的后果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Current drug safety
Current drug safety PHARMACOLOGY & PHARMACY-
CiteScore
2.10
自引率
0.00%
发文量
112
期刊介绍: Current Drug Safety publishes frontier articles on all the latest advances on drug safety. The journal aims to publish the highest quality research articles, reviews and case reports in the field. Topics covered include: adverse effects of individual drugs and drug classes, management of adverse effects, pharmacovigilance and pharmacoepidemiology of new and existing drugs, post-marketing surveillance. The journal is essential reading for all researchers and clinicians involved in drug safety.
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