Automated Detection of Neurological and Mental Health Disorders Using EEG Signals and Artificial Intelligence: A Systematic Review

Hakan Uyanik, Abdulkadir Sengur, Massimo Salvi, Ru‐San Tan, Jen Hong Tan, U. Rajendra Acharya
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Abstract

Mental and neurological disorders significantly impact global health. This systematic review examines the use of artificial intelligence (AI) techniques to automatically detect these conditions using electroencephalography (EEG) signals. Guided by Preferred Reporting Items for Systematic Reviews and Meta‐Analysis (PRISMA), we reviewed 74 carefully selected studies published between 2013 and August 2024 that used machine learning (ML), deep learning (DL), or both of these two methods to detect neurological and mental health disorders automatically using EEG signals. The most common and most prevalent neurological and mental health disorder types were sourced from major databases, including Scopus, Web of Science, Science Direct, PubMed, and IEEE Xplore. Epilepsy, depression, and Alzheimer's disease are the most studied conditions that meet our evaluation criteria, 32, 12, and 10 studies were identified on these topics, respectively. Conversely, the number of studies meeting our criteria regarding stress, schizophrenia, Parkinson's disease, and autism spectrum disorders was relatively more average: 6, 4, 3, and 3, respectively. The diseases that least met our evaluation conditions were one study each of seizure, stroke, anxiety diseases, and one study examining Alzheimer's disease and epilepsy together. Support Vector Machines (SVM) were most widely used in ML methods, while Convolutional Neural Networks (CNNs) dominated DL approaches. DL methods generally outperformed traditional ML, as they yielded higher performance using huge EEG data. We observed that the complex decision process during feature extraction from EEG signals in ML‐based models significantly impacted results, while DL‐based models handled this more efficiently. AI‐based EEG analysis shows promise for automated detection of neurological and mental health conditions. Future research should focus on multi‐disease studies, standardizing datasets, improving model interpretability, and developing clinical decision support systems to assist in the diagnosis and treatment of these disorders.
利用脑电图信号和人工智能自动检测神经和精神健康障碍:系统综述
精神和神经疾病严重影响全球健康。本系统综述探讨了使用人工智能(AI)技术使用脑电图(EEG)信号自动检测这些情况。在系统评价和Meta分析首选报告项目(PRISMA)的指导下,我们回顾了2013年至2024年8月期间发表的74项精心挑选的研究,这些研究使用机器学习(ML)、深度学习(DL)或这两种方法同时使用脑电图信号自动检测神经和精神健康障碍。最常见和最流行的神经和精神健康障碍类型来自主要数据库,包括Scopus, Web of Science, Science Direct, PubMed和IEEE explore。癫痫、抑郁症和阿尔茨海默病是研究最多的条件,符合我们的评估标准,分别有32、12和10项研究确定了这些主题。相反,在压力、精神分裂症、帕金森病和自闭症谱系障碍方面符合我们标准的研究数量相对来说更为平均:分别为6、4、3和3。最不符合我们评估条件的疾病是癫痫、中风、焦虑症各一项研究,以及阿尔茨海默病和癫痫的一项研究。支持向量机(SVM)在ML方法中应用最为广泛,而卷积神经网络(cnn)在DL方法中占主导地位。深度学习方法通常优于传统的机器学习,因为它们使用大量的EEG数据产生了更高的性能。我们观察到,在基于ML的模型中,从EEG信号中提取特征的复杂决策过程显著影响结果,而基于DL的模型处理这一问题更有效。基于人工智能的脑电图分析显示了神经和精神健康状况自动检测的前景。未来的研究应侧重于多疾病研究,标准化数据集,提高模型可解释性,并开发临床决策支持系统,以协助这些疾病的诊断和治疗。
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