Current role of extracorporeal membrane oxygenation for the management of trauma patients: Indications and results.

Mohammed Abdulrahman, Maryam Makki, Malak Bentaleb, Dana Khamis Altamimi, Marcelo Af Ribeiro Junior
{"title":"Current role of extracorporeal membrane oxygenation for the management of trauma patients: Indications and results.","authors":"Mohammed Abdulrahman, Maryam Makki, Malak Bentaleb, Dana Khamis Altamimi, Marcelo Af Ribeiro Junior","doi":"10.5492/wjccm.v14.i1.96694","DOIUrl":null,"url":null,"abstract":"<p><p>Extracorporeal membrane oxygenation (ECMO) has emerged as a vital circulatory life support measure for patients with critical cardiac or pulmonary conditions unresponsive to conventional therapies. ECMO allows blood to be extracted from a patient and introduced to a machine that oxygenates blood and removes carbon dioxide. This blood is then reintroduced into the patient's circulatory system. This process makes ECMO essential for treating various medical conditions, both as a standalone therapy and as adjuvant therapy. Veno-venous (VV) ECMO primarily supports respiratory function and indicates respiratory distress. Simultaneously, veno-arterial (VA) ECMO provides hemodynamic and respiratory support and is suitable for cardiac-related complications. This study reviews recent literature to elucidate the evolving role of ECMO in trauma care, considering its procedural intricacies, indications, contraindications, and associated complications. Notably, the use of ECMO in trauma patients, particularly for acute respiratory distress syndrome and cardiogenic shock, has demonstrated promising outcomes despite challenges such as anticoagulation management and complications such as acute kidney injury, bleeding, thrombosis, and hemolysis. Some studies have shown that VV ECMO was associated with significantly higher survival rates than conventional mechanical ventilation, whereas other studies have reported that VA ECMO was associated with lower survival rates than VV ECMO. ECMO plays a critical role in managing trauma patients, particularly those with acute respiratory failure. Further research is necessary to explore the full potential of ECMO in trauma care. Clinicians should have a clear understanding of the indications and contraindications for the use of ECMO to maximize its benefits in treating trauma patients.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":"14 1","pages":"96694"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671839/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"世界危重病急救学杂志(英文版)","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5492/wjccm.v14.i1.96694","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Extracorporeal membrane oxygenation (ECMO) has emerged as a vital circulatory life support measure for patients with critical cardiac or pulmonary conditions unresponsive to conventional therapies. ECMO allows blood to be extracted from a patient and introduced to a machine that oxygenates blood and removes carbon dioxide. This blood is then reintroduced into the patient's circulatory system. This process makes ECMO essential for treating various medical conditions, both as a standalone therapy and as adjuvant therapy. Veno-venous (VV) ECMO primarily supports respiratory function and indicates respiratory distress. Simultaneously, veno-arterial (VA) ECMO provides hemodynamic and respiratory support and is suitable for cardiac-related complications. This study reviews recent literature to elucidate the evolving role of ECMO in trauma care, considering its procedural intricacies, indications, contraindications, and associated complications. Notably, the use of ECMO in trauma patients, particularly for acute respiratory distress syndrome and cardiogenic shock, has demonstrated promising outcomes despite challenges such as anticoagulation management and complications such as acute kidney injury, bleeding, thrombosis, and hemolysis. Some studies have shown that VV ECMO was associated with significantly higher survival rates than conventional mechanical ventilation, whereas other studies have reported that VA ECMO was associated with lower survival rates than VV ECMO. ECMO plays a critical role in managing trauma patients, particularly those with acute respiratory failure. Further research is necessary to explore the full potential of ECMO in trauma care. Clinicians should have a clear understanding of the indications and contraindications for the use of ECMO to maximize its benefits in treating trauma patients.

目前体外膜氧合在创伤患者治疗中的作用:适应症和结果。
体外膜氧合(ECMO)已成为对常规治疗无反应的危重心脏或肺部疾病患者的重要循环生命支持措施。ECMO允许从病人身上提取血液,并将其引入给血液充氧和去除二氧化碳的机器。然后,这些血液被重新引入病人的循环系统。这一过程使得ECMO对于治疗各种疾病至关重要,无论是作为独立治疗还是辅助治疗。静脉-静脉(VV) ECMO主要支持呼吸功能并提示呼吸窘迫。同时,静脉-动脉(VA) ECMO提供血流动力学和呼吸支持,适用于心脏相关并发症。本研究回顾了最近的文献,以阐明ECMO在创伤护理中的演变作用,考虑到其程序复杂性、适应症、禁忌症和相关并发症。值得注意的是,尽管存在抗凝管理和急性肾损伤、出血、血栓形成和溶血等并发症等挑战,但在创伤患者,特别是急性呼吸窘迫综合征和心源性休克患者中使用ECMO已显示出良好的结果。一些研究表明,VV ECMO的生存率明显高于常规机械通气,而另一些研究报道,VA ECMO的生存率低于VV ECMO。ECMO在治疗创伤患者,特别是急性呼吸衰竭患者中起着至关重要的作用。进一步研究ECMO在创伤护理中的全部潜力是必要的。临床医生应该清楚地了解ECMO的适应症和禁忌症,以最大限度地发挥其治疗创伤患者的益处。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
216
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信