Pathogenesis and targets in uveitis

IF 4.6 2区医学 Q1 RHEUMATOLOGY

Seminars in arthritis and rheumatism Pub Date : 2025-03-02 DOI:10.1016/j.semarthrit.2025.152692

Professor Athimalaipet V Ramanan

引用次数: 0

Abstract

Uveitis is the most common ocular finding in systemic rheumatic diseases. It is a potentially sight threatening disease seen on its own or in association with systemic rheumatic diseases. Whilst significant advances have been made with biological and small molecular therapies for conditions such as rheumatoid arthritis (RA), ankylosing spondylisitis (AS), juvenile idiopathic arthritis (JIA) and psoriatic arthritis (PsA), the evidence base for managing the ocular complications from these diseases, particularly uveitis, is still limited.

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葡萄膜炎的发病机制和靶点。

葡萄膜炎是全身性风湿病中最常见的眼部表现。它是一种潜在的视力威胁疾病，单独或与系统性风湿病相关。虽然类风湿性关节炎（RA）、强直性脊柱炎（as）、青少年特发性关节炎（JIA）和银屑病关节炎（PsA）等疾病的生物和小分子治疗取得了重大进展，但治疗这些疾病（尤其是葡萄膜炎）的眼部并发症的证据基础仍然有限。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Seminars in arthritis and rheumatism 医学-风湿病学

CiteScore

9.20

自引率

4.00%

发文量

176

审稿时长

46 days

期刊介绍： Seminars in Arthritis and Rheumatism provides access to the highest-quality clinical, therapeutic and translational research about arthritis, rheumatology and musculoskeletal disorders that affect the joints and connective tissue. Each bimonthly issue includes articles giving you the latest diagnostic criteria, consensus statements, systematic reviews and meta-analyses as well as clinical and translational research studies. Read this journal for the latest groundbreaking research and to gain insights from scientists and clinicians on the management and treatment of musculoskeletal and autoimmune rheumatologic diseases. The journal is of interest to rheumatologists, orthopedic surgeons, internal medicine physicians, immunologists and specialists in bone and mineral metabolism.