Medication Prescribing Patterns at a Youth Mental Health Service: A Single Center Retrospective Cross-sectional Study.

IF 1.5 4区 医学 Q2 PEDIATRICS
Angela Dinh, Sarira El-Den, Jack C Collins, Blake Hamilton, Connie M S Janiszewski, Donna Fowler, Claire L O'Reilly
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Abstract

Objective: Rates of mental illness among young people remain elevated, and the utilization of youth mental health services is expected to increase. Yet, there is limited knowledge on real-world medication usage and prescribing at these services. Hence, the aim of this study was to explore the medication prescribing patterns at a headspace center, an Australian youth mental health service. Methods: A retrospective cross-sectional study of medical records was conducted. Demographic data, clinical information, prescribed medications, and reasons for use of young people who attended an intake assessment at headspace Camperdown over a 13-month period, February 2021-February 2022, were analyzed. Data collection focused on medication molecule, strength, dose, prescriber designation, and indication. Data were analyzed descriptively. Results: Records for 608 participants were included. The median age at intake was 19.9 years old (interquartile range: 16.1-22.4), and most participants identified as female (n = 372, 61.2%). Anxiety (n = 246, 40.5%) and low mood (n = 95, 15.6%) were the most common presenting concerns. Almost half of participants (n = 291, 47.9%) reported using medication/s at intake, and almost one in five participants (n = 119, 19.6%) were prescribed a medication at the service. The most prescribed medications at headspace were melatonin (24.0%) and quetiapine (12.3%), as well as the antidepressants escitalopram (15.1%), sertraline (11.2%), and fluoxetine (7.3%). Conclusions: This study provides insights into the prescribing practices at a single headspace center. Further investigations are needed to explore the impacts of off-label prescribing for young people, particularly in relation to melatonin and quetiapine, where safety and efficacy in young people have not been well established.

青少年心理健康服务的药物处方模式:一项单中心回顾性横断面研究。
目的:青少年心理疾病的发病率居高不下,青少年心理健康服务的使用率预计会增加。然而,人们对真实世界的药物使用和这些服务的处方了解有限。因此,本研究的目的是探讨在一个顶空间中心,澳大利亚青少年心理健康服务的药物处方模式。方法:对病历资料进行回顾性横断面研究。对2021年2月至2022年2月13个月期间参加headspace Camperdown摄入评估的年轻人的人口统计数据、临床信息、处方药和使用原因进行了分析。数据收集的重点是药物分子、强度、剂量、处方指定和适应症。对数据进行描述性分析。结果:纳入608名参与者的记录。摄入时的中位年龄为19.9岁(四分位数范围:16.1-22.4),大多数参与者为女性(n = 372, 61.2%)。焦虑(n = 246, 40.5%)和情绪低落(n = 95, 15.6%)是最常见的表现。几乎一半的参与者(n = 291, 47.9%)报告在入院时使用药物,几乎五分之一的参与者(n = 119, 19.6%)在服务中处方药物。最常见的处方药是褪黑素(24.0%)和喹硫平(12.3%),以及抗抑郁药艾司西酞普兰(15.1%)、舍曲林(11.2%)和氟西汀(7.3%)。结论:本研究为单一顶空中心的处方实践提供了见解。需要进一步的调查来探索标签外处方对年轻人的影响,特别是与褪黑激素和喹硫平相关的药物,这些药物对年轻人的安全性和有效性尚未得到很好的确定。
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来源期刊
CiteScore
3.60
自引率
5.30%
发文量
61
审稿时长
>12 weeks
期刊介绍: Journal of Child and Adolescent Psychopharmacology (JCAP) is the premier peer-reviewed journal covering the clinical aspects of treating this patient population with psychotropic medications including side effects and interactions, standard doses, and research on new and existing medications. The Journal includes information on related areas of medical sciences such as advances in developmental pharmacokinetics, developmental neuroscience, metabolism, nutrition, molecular genetics, and more. Journal of Child and Adolescent Psychopharmacology coverage includes: New drugs and treatment strategies including the use of psycho-stimulants, selective serotonin reuptake inhibitors, mood stabilizers, and atypical antipsychotics New developments in the diagnosis and treatment of ADHD, anxiety disorders, schizophrenia, autism spectrum disorders, bipolar disorder, eating disorders, along with other disorders Reports of common and rare Treatment Emergent Adverse Events (TEAEs) including: hyperprolactinemia, galactorrhea, weight gain/loss, metabolic syndrome, dyslipidemia, switching phenomena, sudden death, and the potential increase of suicide. Outcomes research.
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