Filling the gaps to empower regional centres to manage myelodysplastic syndrome and acute myeloid leukaemia leading to wider cancer healthcare delivery and access to clinical trials.

IF 1.8 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Michael Ashby, Shaun Fleming, Andrew Spencer, Anne Woollett, Tricia Wright
{"title":"Filling the gaps to empower regional centres to manage myelodysplastic syndrome and acute myeloid leukaemia leading to wider cancer healthcare delivery and access to clinical trials.","authors":"Michael Ashby, Shaun Fleming, Andrew Spencer, Anne Woollett, Tricia Wright","doi":"10.1111/imj.70011","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The management of patients with haematological malignancies in rural and regional Australia is different to that in metropolitan centres due to many factors. Lower-intensity and easier-to-access treatments that are now available for acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS) have improved the deliverability of treatment options for these disorders. Despite the challenges, urgent work is required to allow the care and outcomes of these patients to mirror those living in metropolitan centres.</p><p><strong>Aims: </strong>To highlight the challenges in management of AML and MDS in regional Victoria.</p><p><strong>Methods: </strong>Four clinical cases describing the difficulties faced in the management of AML/MDS patients in regional Victoria.</p><p><strong>Results: </strong>We describe limitations in inpatient services, supportive care, blood product access and both specialised diagnostics and specialist workforce. Access to clinical trials is limited but vital to allow the availability of all therapeutic options.</p><p><strong>Conclusions: </strong>Limitations in management of AML/MDS patients exist in regional centres. We utilised focused clinical fellows in a partnership between Latrobe Regional Health and Alfred Health in Victoria to improve treatment options for these patients. Moreover, we demonstrate future areas of focus, which will further enable rural and regional healthcare providers to bridge the gap in the care of patients with haematological malignancies.</p>","PeriodicalId":13625,"journal":{"name":"Internal Medicine Journal","volume":" ","pages":""},"PeriodicalIF":1.8000,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Internal Medicine Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/imj.70011","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0

Abstract

Background: The management of patients with haematological malignancies in rural and regional Australia is different to that in metropolitan centres due to many factors. Lower-intensity and easier-to-access treatments that are now available for acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS) have improved the deliverability of treatment options for these disorders. Despite the challenges, urgent work is required to allow the care and outcomes of these patients to mirror those living in metropolitan centres.

Aims: To highlight the challenges in management of AML and MDS in regional Victoria.

Methods: Four clinical cases describing the difficulties faced in the management of AML/MDS patients in regional Victoria.

Results: We describe limitations in inpatient services, supportive care, blood product access and both specialised diagnostics and specialist workforce. Access to clinical trials is limited but vital to allow the availability of all therapeutic options.

Conclusions: Limitations in management of AML/MDS patients exist in regional centres. We utilised focused clinical fellows in a partnership between Latrobe Regional Health and Alfred Health in Victoria to improve treatment options for these patients. Moreover, we demonstrate future areas of focus, which will further enable rural and regional healthcare providers to bridge the gap in the care of patients with haematological malignancies.

填补空白,使区域中心能够管理骨髓增生异常综合征和急性髓性白血病,从而扩大癌症医疗保健服务和临床试验。
背景:由于许多因素,澳大利亚农村和地区血液恶性肿瘤患者的管理与大城市中心不同。目前可用于急性髓性白血病(AML)和骨髓增生异常综合征(MDS)的低强度和更容易获得的治疗方法提高了这些疾病治疗方案的可交付性。尽管存在这些挑战,但仍需要紧急开展工作,使这些患者的护理和结果与生活在大都市中心的患者相一致。目的:强调在维多利亚地区AML和MDS管理的挑战。方法:收集维多利亚地区AML/MDS患者的4例临床病例。结果:我们描述了住院服务、支持性护理、血液制品获取以及专业诊断和专家劳动力方面的限制。临床试验的可及性是有限的,但对于提供所有治疗方案至关重要。结论:区域性中心对AML/MDS患者的管理存在局限性。我们利用拉特罗布地区卫生和维多利亚阿尔弗雷德卫生合作伙伴关系的重点临床研究员来改善这些患者的治疗选择。此外,我们展示了未来的重点领域,这将进一步使农村和区域医疗保健提供者能够弥合血液系统恶性肿瘤患者护理方面的差距。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Internal Medicine Journal
Internal Medicine Journal 医学-医学:内科
CiteScore
3.50
自引率
4.80%
发文量
600
审稿时长
3-6 weeks
期刊介绍: The Internal Medicine Journal is the official journal of the Adult Medicine Division of The Royal Australasian College of Physicians (RACP). Its purpose is to publish high-quality internationally competitive peer-reviewed original medical research, both laboratory and clinical, relating to the study and research of human disease. Papers will be considered from all areas of medical practice and science. The Journal also has a major role in continuing medical education and publishes review articles relevant to physician education.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信