Jonathan Hindmarsh , Scott Crowe , Julia Johnson , Chandrima Sengupta , Jemma Walsh , Sonja Dieterich , Jeremy Booth , Paul Keall
{"title":"A dosimetric comparison of helical tomotherapy treatment delivery with real-time adaption and no motion correction","authors":"Jonathan Hindmarsh , Scott Crowe , Julia Johnson , Chandrima Sengupta , Jemma Walsh , Sonja Dieterich , Jeremy Booth , Paul Keall","doi":"10.1016/j.phro.2025.100741","DOIUrl":null,"url":null,"abstract":"<div><div>This study assesses the ability of a helical tomotherapy system equipped with kV imaging and optical surface guidance to adapt to motion traces in real-time. To assess the delivery accuracy with motion, a unified testing framework was used. The average 2 %/2 mm γ-fail rates across all lung traces were 0.1 % for motion adapted and 17.4 % for no motion correction. Average 2 %/2 mm γ-fail rates across all prostate traces were 0.4 % for motion adapted and 12.2 % for no motion correction. Real-time motion adaption was shown to improve the accuracy of dose delivered to a moving phantom compared with no motion adaption.</div><div><strong>MeSH Keywords:</strong> Radiotherapy, image-guided; Radiation therapy, targeted.</div></div>","PeriodicalId":36850,"journal":{"name":"Physics and Imaging in Radiation Oncology","volume":"34 ","pages":"Article 100741"},"PeriodicalIF":3.4000,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physics and Imaging in Radiation Oncology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2405631625000466","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
This study assesses the ability of a helical tomotherapy system equipped with kV imaging and optical surface guidance to adapt to motion traces in real-time. To assess the delivery accuracy with motion, a unified testing framework was used. The average 2 %/2 mm γ-fail rates across all lung traces were 0.1 % for motion adapted and 17.4 % for no motion correction. Average 2 %/2 mm γ-fail rates across all prostate traces were 0.4 % for motion adapted and 12.2 % for no motion correction. Real-time motion adaption was shown to improve the accuracy of dose delivered to a moving phantom compared with no motion adaption.
本研究评估了配备千伏成像和光学表面引导的螺旋断层治疗系统实时适应运动轨迹的能力。采用统一的测试框架来评估带运动的投放精度。所有肺道的平均2% /2 mm γ-失败率为运动适应组为0.1%,无运动纠正组为17.4%。所有前列腺迹线的平均2% /2 mm γ-失败率为运动适应组为0.4%,无运动矫正组为12.2%。与没有运动适应相比,实时运动适应可以提高给药的准确性。关键词:放射治疗;图像引导;有针对性的放射治疗。