Association of immediate symmetrizing oncoplastic surgery with patient-reported outcomes in patients with breast cancer – A retrospective cohort study

IF 2.7 3区医学 Q1 SURGERY

American journal of surgery Pub Date : 2025-03-04 DOI:10.1016/j.amjsurg.2025.116286

Martin Heidinger , Gilles Bilfeld , Nico Föge , Julie M. Loesch , Nadia Maggi , Rama Kiblawi , Ruth S. Eller , Marie Louise Frevert , Fabienne D. Schwab , Christian Kurzeder , Tibor A. Zwimpfer , Walter P. Weber

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Abstract

Introduction

Oncoplastic breast surgery (OPS) with immediate symmetrization is commonly performed. However, its impact on patient-reported outcomes (PROs) remains uncertain.

Methods

Patients with stage 0-III breast cancer who underwent OPS (including oncoplastic breast conserving surgery, or nipple- or skin-sparing mastectomy) at a Swiss university hospital between 01/2013-12/2023 who completed a postoperative BREAST-Q questionnaire were identified from a prospectively maintained database. A generalized linear model was used to detect differences in PROs between those who underwent unilateral versus immediate symmetrizing surgery.

Results

Of 441 eligible patients, 333 (75.5 %) underwent unilateral OPS, while 108 (24.5 %) underwent bilateral OPS. Median time to PRO assessment was 35.1 months (Q1-Q3 13.4–49.5). No differences in PROs were identified between patients who underwent unilateral versus bilateral OPS. Short-term surgical morbidity was more common in patients who underwent symmetrizing surgery, which negatively impacted PROs.

Conclusion

The present study did not demonstrate any impact of immediate symmetrization on PROs.

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来源期刊

American journal of surgery 医学-外科

CiteScore

5.00

自引率

6.70%

发文量

570

审稿时长

56 days

期刊介绍： The American Journal of Surgery® is a peer-reviewed journal designed for the general surgeon who performs abdominal, cancer, vascular, head and neck, breast, colorectal, and other forms of surgery. AJS is the official journal of 7 major surgical societies* and publishes their official papers as well as independently submitted clinical studies, editorials, reviews, brief reports, correspondence and book reviews.