Predictive factors of mortality in patients with abdominal trauma.

Ömer Faruk Turan, Didem Çankaya Gökdere, Murat Genç, Bensu Bulut, Medine Akkanöz, Hüseyin Mutlu, Ramiz Yazıcı
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Abstract

Background: Traumatic injuries, particularly abdominal trauma, are a major cause of mortality worldwide. This study aimed to evaluate predictive factors for mortality and morbidity in abdominal trauma patients using simple, rapid, and accessible clinical and laboratory parameters, with a focus on developing scoring systems for emergency department decision-making.

Methods: A retrospective cohort study was conducted in a Level 1 Trauma Center between October 2022 and March 2024. Patients aged 18 and older with abdominal trauma or multi-trauma were included, while cases with incomplete records, known chronic diseases, or a recent trauma history were excluded. Data on demographics, vital signs, laboratory results, imaging findings, clinical scores, and outcomes were collected. Logistic regression and receiver operating characteristic (ROC) analyses were performed to identify independent mortality predictors and their cut-off values.

Results: Out of 693 patients, the mortality rate was 3.6%. The most common mechanisms of trauma were road traffic accidents (59.3%) and falls (23.4%). Independent predictors of mortality included age ≥54 years, Glasgow Coma Scale (GCS) ≤14, Injury Severity Score (ISS) ≥24, and Shock Index ≥1.08. ROC analysis revealed that GCS had the highest predictive value for mortality (area under the curve [AUC]: 0.828), followed by ISS, age, and Shock Index. Elevated levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate, and creatinine were associated with worse outcomes, aligning with findings in the literature.

Conclusion: Age, GCS, ISS, and Shock Index are strong predictors of mortality in abdominal trauma patients. Integrating these parameters into clinical decision-making can enhance risk stratification and improve patient management. Prospective multicenter studies and national trauma registries are necessary to refine trauma care and reduce mortality rates.

腹部创伤患者死亡率的预测因素。
背景:创伤性损伤,特别是腹部创伤,是世界范围内死亡的主要原因。本研究旨在利用简单、快速、可获得的临床和实验室参数评估腹部创伤患者死亡率和发病率的预测因素,重点是开发评分系统,以供急诊科决策。方法:于2022年10月至2024年3月在某一级创伤中心进行回顾性队列研究。年龄在18岁及以上的腹部创伤或多重创伤患者被纳入,而记录不完整、已知慢性疾病或近期创伤史的患者被排除在外。收集了人口统计学、生命体征、实验室结果、影像学表现、临床评分和结果的数据。采用Logistic回归和受试者工作特征(ROC)分析来确定独立的死亡率预测因子及其临界值。结果:693例患者中,死亡率为3.6%。最常见的创伤机制是道路交通事故(59.3%)和跌倒(23.4%)。死亡率的独立预测因素包括年龄≥54岁,格拉斯哥昏迷评分(GCS)≤14,损伤严重程度评分(ISS)≥24,休克指数≥1.08。ROC分析显示,GCS对死亡率的预测价值最高(曲线下面积[AUC]: 0.828),其次是ISS、年龄和休克指数。谷丙转氨酶(ALT)、天冬氨酸转氨酶(AST)、乳酸和肌酐水平升高与较差的预后相关,这与文献研究结果一致。结论:年龄、GCS、ISS和休克指数是腹部创伤患者死亡率的重要预测因子。将这些参数纳入临床决策可以加强风险分层,改善患者管理。前瞻性多中心研究和国家创伤登记是完善创伤护理和降低死亡率的必要条件。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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