Jaeha Lee, Si Yeol Song, Young Seob Shin, Sung-Woo Kim, Ye Jin Yoo, Ji Hyeon Joo, Ho-Seok Sa, Dok Hyun Yoon, Sang-Wook Lee
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引用次数: 0
Abstract
This study evaluated the efficacy and safety of 20.0 Gy versus 30.6 Gy radiotherapy for conjunctival MALT lymphoma in 76 lesions treated between 2010 and 2022. The 30.6 Gy group showed a shorter median time to response (3.7 vs. 9.5 months, p < 0.001) and a higher complete response rate at 6 months (68.4% vs. 36.8%, p = 0.009). However, both doses achieved 100% local control at two years. Radiation-induced complications were minimal, with no grade 3 or higher events, and cataracts occurred in only 5.3% of patients in both groups. These results indicate that reducing the radiation dose to 20.0 Gy can achieve comparable long-term outcomes with minimal toxicity, offering an effective treatment alternative for localized conjunctival MALT lymphoma.
期刊介绍：
Leukemia & Lymphoma in its fourth decade continues to provide an international forum for publication of high quality clinical, translational, and basic science research, and original observations relating to all aspects of hematological malignancies. The scope ranges from clinical and clinico-pathological investigations to fundamental research in disease biology, mechanisms of action of novel agents, development of combination chemotherapy, pharmacology and pharmacogenomics as well as ethics and epidemiology. Submissions of unique clinical observations or confirmatory studies are considered and published as Letters to the Editor
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