Multi-institutional study on image quality for a novel CBCT solution on O-ring linac.

IF 2 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Luis Agulles-Pedrós, R Lee MacDonald, Amanda Jean Cherpak, Nayha Dixit, Lei Dong, Tianyu Zhao, Kundan Thind, Anthony Doemer, Boon-Keng Teo, Shiqin Su, Alexander Moncion, James L Robar
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引用次数: 0

Abstract

Introduction: This work presents a multi-institutional study on image quality provided by a novel cone beam computed tomography (CBCT). The main goal is to investigate the consistency of imaging performance across multiple institutions.

Methods: Phantoms for measuring relative electron density (RED) and image quality were sent to six institutions for imaging on Ethos and Halcyon units equipped with HyperSight CBCT. The imaging protocols included tube potential from 100 to 140 kVp and exposure from 80 to 800 mAs. Imaging performance was evaluated with regard to RED versus Hounsfield units (HU), uniformity, contrast-to-noise ratio (CNR), slice thickness, circular symmetry, modulation transfer function (MTF), and spatial resolution.

Results: Among all institutions, some variability was observed among institutions in the RED-to-HU relationship, especially for RED values greater than 1, although no outliers were found (|z-score| < 2 in all cases). In this range, RED/HU slopes were 475 ± 25 10-6 RED/HU at 100kVp, 505 ± 20 10-6 RED/HU at 125kVp, and 550 ± 20 10-6 RED/HU at 140kVp. Radial uniformity ranged from 1 to 7 HU, depending on protocol. Circular symmetry for two points 50 mm apart showed consistency within one-pixel dimension. Integral nonuniformity was between 1 and 10, with no difference observed between vertical and horizontal dimensions. Contrast rods with 1% gave CNR = 0.5, 1 and 2 for 100(88), 125(176), and 140(528) in kVp(mAs), and contrast rods with 0.5% had CNR = 0.2, 0.4 and 0.8 for 100(88), 125(176), and 140(528) in kVp(mAs). Spatial resolution given by MTF at 10% and 50% yielded values of 0.55 ± 0.01 mm-1 and 0.35 ± 0.02 mm-1, respectively.

Conclusions: This multi-institutional analysis of CBCT imaging performance showed consistency in radial uniformity, circular symmetry, integral nonuniformity, contrast, and spatial resolution. Some variability was seen in the RED-to-HU relationship for RED > 1 depending on exposure. More data from different institutions would be necessary to establish more robust statistical metrics, which ensure quality parameters.

o形环直线加速器新型CBCT解图像质量的多机构研究。
本工作介绍了一项由新型锥束计算机断层扫描(CBCT)提供的图像质量的多机构研究。主要目标是调查多个机构成像性能的一致性。方法:将用于测量相对电子密度(RED)和图像质量的幻影送至六个机构,在配备HyperSight CBCT的Ethos和Halcyon设备上进行成像。成像方案包括100至140 kVp的管电位和80至800 ma的暴露。成像性能根据RED与Hounsfield单位(HU)、均匀性、对比噪声比(CNR)、切片厚度、圆对称性、调制传递函数(MTF)和空间分辨率进行评估。结果:在所有机构中,各机构之间的RED-to-HU关系存在一定的变异性,特别是在RED值大于1时,尽管没有发现异常值(100kVp时,|z-score| -6 RED/HU, 125kVp时,505±20 10-6 RED/HU,以及140kVp时,550±20 10-6 RED/HU)。径向均匀度范围从1到7 HU,取决于协议。相距50mm的两点的圆对称在一个像素维度内表现出一致性。整体非均匀性在1 ~ 10之间,垂直和水平维度之间没有差异。1%对比棒对100(88)、125(176)和140(528)kVp(mAs)的CNR分别为0.5、1和2,0.5%对比棒对100(88)、125(176)和140(528)kVp(mAs)的CNR分别为0.2、0.4和0.8。MTF在10%和50%条件下的空间分辨率分别为0.55±0.01 mm-1和0.35±0.02 mm-1。结论:该多机构的CBCT成像性能分析显示,在径向均匀性、圆对称性、整体非均匀性、对比度和空间分辨率方面具有一致性。RED bbbb1的RED-to- hu关系因暴露程度不同而有所差异。需要来自不同机构的更多数据来建立更可靠的统计指标,以确保质量参数。
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来源期刊
CiteScore
3.60
自引率
19.00%
发文量
331
审稿时长
3 months
期刊介绍: Journal of Applied Clinical Medical Physics is an international Open Access publication dedicated to clinical medical physics. JACMP welcomes original contributions dealing with all aspects of medical physics from scientists working in the clinical medical physics around the world. JACMP accepts only online submission. JACMP will publish: -Original Contributions: Peer-reviewed, investigations that represent new and significant contributions to the field. Recommended word count: up to 7500. -Review Articles: Reviews of major areas or sub-areas in the field of clinical medical physics. These articles may be of any length and are peer reviewed. -Technical Notes: These should be no longer than 3000 words, including key references. -Letters to the Editor: Comments on papers published in JACMP or on any other matters of interest to clinical medical physics. These should not be more than 1250 (including the literature) and their publication is only based on the decision of the editor, who occasionally asks experts on the merit of the contents. -Book Reviews: The editorial office solicits Book Reviews. -Announcements of Forthcoming Meetings: The Editor may provide notice of forthcoming meetings, course offerings, and other events relevant to clinical medical physics. -Parallel Opposed Editorial: We welcome topics relevant to clinical practice and medical physics profession. The contents can be controversial debate or opposed aspects of an issue. One author argues for the position and the other against. Each side of the debate contains an opening statement up to 800 words, followed by a rebuttal up to 500 words. Readers interested in participating in this series should contact the moderator with a proposed title and a short description of the topic
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