Primary cutaneous CD8-positive T-cell lymphoma-granulomatous mycosis fungoides: A rare case report.

Abstract

Granulomatous mycosis fungoides (GMF) is a rare subtype of T-cell cutaneous lymphoma. Due to the lack of distinct clinical features, GMF may pose a diagnostic challenge, which results in diagnostic delay. The diagnosis is based on histopathological and immunohistochemical findings. Herein, we present an 82-year-old male with itchy lesions over the scalp, face, forearms, trunk, and bilateral lower limbs for 6 months. Histologically, it was a CD8-positive GMF. GMF is a rare subtype of mycosis fungoides with <100 cases in the literature, and most of these cases showed a CD4-positive phenotype. CD8-positive GMF is extremely rare. We observed that it commonly affects elderly females. The patients often present with nodules and do not carry an adverse prognosis.