Concurrent Lichen Planopilaris and Female Androgenic Alopecia in Skin of Color: A Case Series.

IF 1.5 4区 医学 Q3 DERMATOLOGY
Eliza Balazic, Hailey Konisky, Eden Axler, Kseniya Kobets
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Abstract

Background: Trichoscopy findings can differ in the skin of color requiring a dedicated approach with adequate examination in order to ensure proper diagnosis and treatment. This case series details three cases of concurrent lichen planopilaris (LPP) and female androgenic alopecia (FAGA) in the skin of color.

Methods: Gross examination of all cases revealed mild to moderate hair density thinning of the temporal and frontal scalp. Trichoscopy was done in all three cases before biopsy. The temporal scalp of each patient showed diffuse hair follicle miniaturization with minimal terminal hairs and brown follicular halos, all findings were consistent with FAGA. However, upon inspection of the frontal scalp, each case revealed findings associated with scarring alopecia including scale, erythema, and peripilar casts in addition to the presence of follicle miniaturization.

Results: In the first two cases, two punch biopsies were taken, one from the temporal scalp and one from the frontal scalp. Temporal biopsy revealed FAGA and frontal biopsy revealed LPP arising in a background of AGA. In the third case, only the frontal scalp was biopsied, which showed LPP in a background of FAGA. All three cases received the same treatment regimen; clobetasol 0.05% solution and minoxidil 5% foam/solution topically for treatment of FAGA and monthly intralesional triamcinolone acetonide for treatment of the LPP.

Conclusion: Our report suggests the importance of total scalp dermoscopy and the need for biopsies in areas with varying dermoscopy findings as opposed to areas with the most significant hair loss. J Drugs Dermatol. 2025;24(3):320-322. doi:10.36849/JDD.7318.

并发扁平毛癣和女性雄激素性脱发的皮肤颜色:一个案例系列。
背景:毛发镜检查结果可能因肤色不同而不同,需要专门的方法进行充分的检查,以确保正确的诊断和治疗。本病例系列详细介绍了三例并发扁平毛衣癣(LPP)和女性雄激素性脱发(FAGA)的皮肤颜色。方法:所有病例的大体检查显示轻度至中度头发密度稀疏的颞部和额部头皮。三例患者活检前均行毛发镜检查。每例患者颞部头皮均表现为弥漫性毛囊缩小,末端毛极少,毛囊晕呈棕色,均与FAGA相符。然而,在检查额部头皮时,每个病例都发现了与瘢痕性脱发相关的发现,包括鳞屑、红斑和毛囊小型化之外的毛囊周围铸型。结果:前2例患者分别在颞部头皮和额部头皮进行了两次穿刺活检。颞部活检显示FAGA,额部活检显示LPP在AGA背景下出现。在第三例中,仅对额部头皮进行了活检,在FAGA背景下显示LPP。所有三个病例接受相同的治疗方案;氯倍他索0.05%溶液和米诺地尔5%泡沫/溶液局部治疗FAGA,每月局部注射曲安奈德治疗LPP。结论:我们的报告提示了全头皮皮肤镜检查的重要性,并且需要在皮肤镜检查结果不同的区域进行活检,而不是在脱发最严重的区域。皮肤医学杂志,2025;24(3):320-322。doi: 10.36849 / JDD.7318。
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来源期刊
CiteScore
2.20
自引率
13.30%
发文量
289
审稿时长
3-6 weeks
期刊介绍: The Journal of Drugs in Dermatology (JDD) is a peer-reviewed publication indexed with MEDLINE®/PubMed® that was founded by the renowned Dr. Perry Robins MD. Founded in 2002, it offers one of the fastest routes to disseminate dermatologic information and is considered the fastest growing publication in dermatology. We present original articles, award-winning case reports, and timely features pertaining to new methods, techniques, drug therapy, and devices in dermatology that provide readers with peer reviewed content of the utmost quality. Our high standards of content are maintained through a balanced, peer-review process. Articles are reviewed by an International Editorial Board of over 160 renowned experts.
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