{"title":"Acute pancreatitis caused by oral contraceptives.","authors":"Yersen Asai, Qiqi Zhang, Liangliang Zheng, Jian Li, Zhiqiang Zhang, Hong Liang Gao","doi":"10.1007/s11739-025-03897-4","DOIUrl":null,"url":null,"abstract":"<p><p>Acute pancreatitis manifests as an inflammatory condition, starting with the acinar cells in the pancreas and gradually escalating to widespread inflammation. Hypertriglyceridemia ranks as the third leading reason for acute pancreatitis, following gallstones and alcohol use, making up 2-14% of instances [1]. Numerous research findings indicate that acute pancreatitis triggered by hypertriglyceridemia (HTG-AP, hypertriglyceridemic acute pancreatitis) may lead to increased death rates compared to other acute pancreatitis causes hypertriglyceridemia, characterized by fasting serum triglycerides exceeding (150mg/dL; 1.7mmol/L), and severe hypertriglyceridemia, identified by levels above (885 mg/dL; > 10 mmol/L) [2]. This paper presents an uncommon instance of HTG-AP, triggered by polycystic ovary syndrome and treated with oral contraceptive Drospirenone and ethinylestradiol tablets, where serum triglyceride levels reached an unprecedented 9906.37 mg/dL.</p>","PeriodicalId":13662,"journal":{"name":"Internal and Emergency Medicine","volume":" ","pages":"529-533"},"PeriodicalIF":3.2000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Internal and Emergency Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11739-025-03897-4","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/6 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Acute pancreatitis manifests as an inflammatory condition, starting with the acinar cells in the pancreas and gradually escalating to widespread inflammation. Hypertriglyceridemia ranks as the third leading reason for acute pancreatitis, following gallstones and alcohol use, making up 2-14% of instances [1]. Numerous research findings indicate that acute pancreatitis triggered by hypertriglyceridemia (HTG-AP, hypertriglyceridemic acute pancreatitis) may lead to increased death rates compared to other acute pancreatitis causes hypertriglyceridemia, characterized by fasting serum triglycerides exceeding (150mg/dL; 1.7mmol/L), and severe hypertriglyceridemia, identified by levels above (885 mg/dL; > 10 mmol/L) [2]. This paper presents an uncommon instance of HTG-AP, triggered by polycystic ovary syndrome and treated with oral contraceptive Drospirenone and ethinylestradiol tablets, where serum triglyceride levels reached an unprecedented 9906.37 mg/dL.
期刊介绍：
Internal and Emergency Medicine (IEM) is an independent, international, English-language, peer-reviewed journal designed for internists and emergency physicians. IEM publishes a variety of manuscript types including Original investigations, Review articles, Letters to the Editor, Editorials and Commentaries. Occasionally IEM accepts unsolicited Reviews, Commentaries or Editorials. The journal is divided into three sections, i.e., Internal Medicine, Emergency Medicine and Clinical Evidence and Health Technology Assessment, with three separate editorial boards. In the Internal Medicine section, invited Case records and Physical examinations, devoted to underlining the role of a clinical approach in selected clinical cases, are also published. The Emergency Medicine section will include a Morbidity and Mortality Report and an Airway Forum concerning the management of difficult airway problems. As far as Critical Care is becoming an integral part of Emergency Medicine, a new sub-section will report the literature that concerns the interface not only for the care of the critical patient in the Emergency Department, but also in the Intensive Care Unit. Finally, in the Clinical Evidence and Health Technology Assessment section brief discussions of topics of evidence-based medicine (Cochrane’s corner) and Research updates are published. IEM encourages letters of rebuttal and criticism of published articles. Topics of interest include all subjects that relate to the science and practice of Internal and Emergency Medicine.
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