Compartmentalization Device of Microenvironment for Analyzing iPSCs Differentiation

IF 0.4 4区工程技术 Q4 ENGINEERING, ELECTRICAL & ELECTRONIC

Electrical Engineering in Japan Pub Date : 2025-01-03 DOI:10.1002/eej.23503

Daiki Fukai, Taro Toyoda, Hidekuni Takao, Fusao Shimokawa, Kyohei Terao

引用次数: 0

Abstract

This paper reports on a microdevice for compartmentalizing the solution microenvironment that can fractionate the space surrounding spheroids during the culture and differentiation processes, with the aim of verifying the effects of cell–cell interactions in the solution microenvironment on iPS cell differentiation. In this paper, we demonstrated that spheroids of iPS cells were successfully formed on the device and fractionated their microenvironment by a detachable compartmentalization frame (DCF) formed by 3D printing technology.

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用于分析iPSCs分化的微环境区隔装置

本文报道了一种用于划分溶液微环境的微装置，该装置可以在培养和分化过程中划分球体周围的空间，目的是验证溶液微环境中细胞-细胞相互作用对iPS细胞分化的影响。在本文中，我们证明了在该设备上成功形成了iPS细胞的球体，并通过3D打印技术形成的可拆卸分隔框架（DCF）对其微环境进行了分离。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Electrical Engineering in Japan 工程技术-工程：电子与电气

CiteScore

0.80

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： Electrical Engineering in Japan (EEJ) is an official journal of the Institute of Electrical Engineers of Japan (IEEJ). This authoritative journal is a translation of the Transactions of the Institute of Electrical Engineers of Japan. It publishes 16 issues a year on original research findings in Electrical Engineering with special focus on the science, technology and applications of electric power, such as power generation, transmission and conversion, electric railways (including magnetic levitation devices), motors, switching, power economics.