Minimally invasive management of Müllerian anomalies in pediatric patients: A retrospective case series and literature review

Abstract

Müllerian anomalies (MA) are structural defects that arise due to alterations in the development of the paramesonephric or Müllerian ducts during the first 16 weeks of gestation. Few cases have been reported on laparoscopic management as a diagnostic and therapeutic method in Müllerian anomalies. This study presents a retrospective case series of 9 patients diagnosed with Müllerian anomalies. A diagnostic approach was performed on 9 patients with suspected Müllerian anomalies, including 3 patients with OHVIRA Syndrome. Of all patients, 8 of them were treated with minimally invasive procedures, and one delayed the treatment. Our findings highlight the importance of employing advanced imaging techniques, such as MRI and UroCT, in complex cases to ensure accurate diagnosis and optimal surgical planning. Our case series demonstrates that most patients can have their condition successfully managed through a minimally invasive approach, as highlighted in the reported cases. Future studies should focus on expanding the clinical evidence base, focusing on long-term follow-up to assess fertility outcomes, quality of life and durability of these surgical interventions.