Outcomes of Oncologic Total Humeral Reconstruction.

IF 1.6 4区医学 Q4 ONCOLOGY

Anticancer research Pub Date : 2025-03-01 DOI:10.21873/anticanres.17494

Leilani Garayua-Cruz, Samuel E Broida, Mikaela H Sullivan, Mark E Morrey, Jonathan D Barlow, Joaquin Sanchez-Sotelo, Matthew T Houdek

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引用次数: 0

Abstract

Background/aim: The humerus is the most common site for malignant tumors in the upper extremity. Rarely, a total humeral resection with combined replacements of both the shoulder and the elbow are necessary. The aim of this study was to evaluate outcomes after total humeral reconstruction at our institution.

Patients and methods: Nine patients (5 females, 4 males, mean age 48±26 years) with a malignant tumor of the humerus were included in this study. This included five endoprostheses and four allograft prosthetic composites.

Results: Postoperative complications occurred in eight patients, most commonly deep vein thrombosis (DVT, n=3) and elbow contractures (n=3). Complications led to a revision procedure in one patient, with a cumulative incidence of failure of 25% at 5-years and a 5-year overall patient survival rate of 13%. At the most recent follow-up, the median Musculoskeletal Tumor Society Score was 50%.

Conclusion: Total humerus reconstruction is a rare surgical procedure that is associated with a high rate of complications with relatively poor functional outcomes. However, this option does offer a means of limb salvage for patients with limited options.

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来源期刊

Anticancer research 医学-肿瘤学

CiteScore

3.70

自引率

10.00%

发文量

566

审稿时长

2 months

期刊介绍： ANTICANCER RESEARCH is an independent international peer-reviewed journal devoted to the rapid publication of high quality original articles and reviews on all aspects of experimental and clinical oncology. Prompt evaluation of all submitted articles in confidence and rapid publication within 1-2 months of acceptance are guaranteed. ANTICANCER RESEARCH was established in 1981 and is published monthly (bimonthly until the end of 2008). Each annual volume contains twelve issues and index. Each issue may be divided into three parts (A: Reviews, B: Experimental studies, and C: Clinical and Epidemiological studies). Special issues, presenting the proceedings of meetings or groups of papers on topics of significant progress, will also be included in each volume. There is no limitation to the number of pages per issue.