"I'm Ready This Time": Investigating physiological and emotional habituation to repetitive social stress.

IF 3.6 2区 心理学 Q1 PSYCHOLOGY, MULTIDISCIPLINARY
Annelise A Madison, M Rosie Shrout, Stephanie J Wilson, Megan E Renna, Juan Peng, Rebecca Andridge, Lisa M Jaremka, Christopher P Fagundes, Martha A Belury, William B Malarkey, Janice K Kiecolt-Glaser
{"title":"\"I'm Ready This Time\": Investigating physiological and emotional habituation to repetitive social stress.","authors":"Annelise A Madison, M Rosie Shrout, Stephanie J Wilson, Megan E Renna, Juan Peng, Rebecca Andridge, Lisa M Jaremka, Christopher P Fagundes, Martha A Belury, William B Malarkey, Janice K Kiecolt-Glaser","doi":"10.1093/abm/kaaf009","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Repetitive stress is at the nexus of acute and chronic stress, and there is limited knowledge about how physiological and emotional responses change with repeated exposure.</p><p><strong>Purpose: </strong>We examined stress-related biomarkers and emotional responses to repeated social stressors, and we tested behavioral moderators.</p><p><strong>Methods: </strong>In Study 1, 42 adults completed the Trier Social Stress Test (TSST) twice, 4 months apart. Serum inflammatory cytokines (interleukin-6 [IL-6], tumor necrosis factor-α [TNF-α]), blood pressure, pulse, salivary cortisol, and state-level anxiety were measured surrounding the stressor. In Study 2, 84 married individuals completed two 20-minute discussions of contentious topics in the marriage, 1 month apart. Serum IL-6, TNF-α, blood pressure, pulse, salivary cortisol, and state affect were collected surrounding the conflict. Trained experimenters rated positive and negative behavior during the conflict.</p><p><strong>Results: </strong>In the repetitive Trier paradigm, participants reported less anxiety (Ps = .048) and had higher anticipatory IL-6 responses (P = .014) at Visit 2, compared to Visit 1. In the repetitive marital conflict paradigm, participants had lower positive affect (P = .0004), as well as systolic blood pressure (SBP) (P = .009), diastolic blood pressure (P = .0003), and pulse (P = .027) habituation at the second visit. Objectively rated negative conflict behavior interacted with visit to predict TNF-α (P = .025) and SBP (P = .037) responses. Positive conflict behavior did not moderate outcomes (Ps > .06).</p><p><strong>Conclusions: </strong>Stress-sensitive systems can habituate or sensitize to even nontraumatic, repetitive social stressors. Patterns of habituation or sensitization may vary by time between repetition, type of social stressor, stress-sensitive system, and participant behavior.</p>","PeriodicalId":7939,"journal":{"name":"Annals of Behavioral Medicine","volume":"59 1","pages":""},"PeriodicalIF":3.6000,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11878534/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Behavioral Medicine","FirstCategoryId":"102","ListUrlMain":"https://doi.org/10.1093/abm/kaaf009","RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHOLOGY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Repetitive stress is at the nexus of acute and chronic stress, and there is limited knowledge about how physiological and emotional responses change with repeated exposure.

Purpose: We examined stress-related biomarkers and emotional responses to repeated social stressors, and we tested behavioral moderators.

Methods: In Study 1, 42 adults completed the Trier Social Stress Test (TSST) twice, 4 months apart. Serum inflammatory cytokines (interleukin-6 [IL-6], tumor necrosis factor-α [TNF-α]), blood pressure, pulse, salivary cortisol, and state-level anxiety were measured surrounding the stressor. In Study 2, 84 married individuals completed two 20-minute discussions of contentious topics in the marriage, 1 month apart. Serum IL-6, TNF-α, blood pressure, pulse, salivary cortisol, and state affect were collected surrounding the conflict. Trained experimenters rated positive and negative behavior during the conflict.

Results: In the repetitive Trier paradigm, participants reported less anxiety (Ps = .048) and had higher anticipatory IL-6 responses (P = .014) at Visit 2, compared to Visit 1. In the repetitive marital conflict paradigm, participants had lower positive affect (P = .0004), as well as systolic blood pressure (SBP) (P = .009), diastolic blood pressure (P = .0003), and pulse (P = .027) habituation at the second visit. Objectively rated negative conflict behavior interacted with visit to predict TNF-α (P = .025) and SBP (P = .037) responses. Positive conflict behavior did not moderate outcomes (Ps > .06).

Conclusions: Stress-sensitive systems can habituate or sensitize to even nontraumatic, repetitive social stressors. Patterns of habituation or sensitization may vary by time between repetition, type of social stressor, stress-sensitive system, and participant behavior.

“这次我准备好了”:调查对重复性社会压力的生理和情感习惯。
背景:重复应激是急性和慢性应激的联系,关于重复暴露如何改变生理和情绪反应的知识有限。目的:我们研究了压力相关的生物标志物和对重复社会压力源的情绪反应,并测试了行为调节因子。方法:在研究1中,42名成人进行了两次特里尔社会压力测试(TSST),间隔4个月。在应激源周围测量血清炎症因子(白细胞介素-6 [IL-6]、肿瘤坏死因子-α [TNF-α])、血压、脉搏、唾液皮质醇和焦虑状态。在研究2中,84名已婚人士完成了两次20分钟的关于婚姻中有争议话题的讨论,间隔一个月。在冲突前后采集血清IL-6、TNF-α、血压、脉搏、唾液皮质醇和状态影响。训练有素的实验者对冲突中的积极和消极行为进行打分。结果:在重复Trier范式中,与访问1相比,访问2时参与者报告的焦虑程度较低(P = 0.048),预期IL-6反应较高(P = 0.014)。在重复婚姻冲突范式中,参与者在第二次访问时具有较低的积极影响(P = 0.0004),以及收缩压(P = 0.009),舒张压(P = 0.0003)和脉搏习惯(P = 0.027)。客观评定的消极冲突行为与来访相互作用预测TNF-α (P = 0.025)和收缩压(P = 0.037)反应。积极的冲突行为对结果没有调节作用(p < 0.05)。结论:压力敏感系统可以适应或敏感,即使是非创伤性的,重复的社会压力源。习惯化或敏化的模式可能因重复、社会压力源类型、压力敏感系统和参与者行为之间的时间而异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Annals of Behavioral Medicine
Annals of Behavioral Medicine PSYCHOLOGY, MULTIDISCIPLINARY-
CiteScore
7.00
自引率
5.30%
发文量
65
期刊介绍: Annals of Behavioral Medicine aims to foster the exchange of knowledge derived from the disciplines involved in the field of behavioral medicine, and the integration of biological, psychosocial, and behavioral factors and principles as they relate to such areas as health promotion, disease prevention, risk factor modification, disease progression, adjustment and adaptation to physical disorders, and rehabilitation. To achieve these goals, much of the journal is devoted to the publication of original empirical articles including reports of randomized controlled trials, observational studies, or other basic and clinical investigations. Integrative reviews of the evidence for the application of behavioral interventions in health care will also be provided. .
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信