Mennatullah Mahmoud , Mohammad Mansour , Hisham M. Elrefai , Amira J. Hamed , Essam A. Rashed
{"title":"Enhanced retinal arteries and veins segmentation through deep learning with conditional random fields","authors":"Mennatullah Mahmoud , Mohammad Mansour , Hisham M. Elrefai , Amira J. Hamed , Essam A. Rashed","doi":"10.1016/j.bspc.2025.107747","DOIUrl":null,"url":null,"abstract":"<div><div>The intricate network of retinal blood vessels serves as a sensitive window into systemic health, offering valuable insights into diseases like diabetic retinopathy. However, unraveling these insights poses challenges due to limitations of traditional visible light fundus photography. Infrared imaging emerges as a transformative tool, enabling deeper tissue penetration and enhanced visualization of the retinal vasculature. Yet, unlocking its full potential hinges on accurate and reliable segmentation of retinal arteries and veins within IR images. This study explores different ways to improve the accurate mapping of blood vessels in the eye using deep learning architectures. We used a special dataset captured with advanced technology to train and test three different models. This study amplifies the dataset’s adaptability, facilitating the training of U-Net, Residual U-Net, and Attention U-Net models. Among these models, the Attention Residual U-Net demonstrated superior segmentation performance, achieving an accuracy of 96.03%, a dice coefficient of 0.882, and a recall of 0.895 after post-processing. This research opens up possibilities for further improvements in eye-related healthcare.</div></div>","PeriodicalId":55362,"journal":{"name":"Biomedical Signal Processing and Control","volume":"106 ","pages":"Article 107747"},"PeriodicalIF":4.9000,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical Signal Processing and Control","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1746809425002587","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
Abstract
The intricate network of retinal blood vessels serves as a sensitive window into systemic health, offering valuable insights into diseases like diabetic retinopathy. However, unraveling these insights poses challenges due to limitations of traditional visible light fundus photography. Infrared imaging emerges as a transformative tool, enabling deeper tissue penetration and enhanced visualization of the retinal vasculature. Yet, unlocking its full potential hinges on accurate and reliable segmentation of retinal arteries and veins within IR images. This study explores different ways to improve the accurate mapping of blood vessels in the eye using deep learning architectures. We used a special dataset captured with advanced technology to train and test three different models. This study amplifies the dataset’s adaptability, facilitating the training of U-Net, Residual U-Net, and Attention U-Net models. Among these models, the Attention Residual U-Net demonstrated superior segmentation performance, achieving an accuracy of 96.03%, a dice coefficient of 0.882, and a recall of 0.895 after post-processing. This research opens up possibilities for further improvements in eye-related healthcare.
期刊介绍:
Biomedical Signal Processing and Control aims to provide a cross-disciplinary international forum for the interchange of information on research in the measurement and analysis of signals and images in clinical medicine and the biological sciences. Emphasis is placed on contributions dealing with the practical, applications-led research on the use of methods and devices in clinical diagnosis, patient monitoring and management.
Biomedical Signal Processing and Control reflects the main areas in which these methods are being used and developed at the interface of both engineering and clinical science. The scope of the journal is defined to include relevant review papers, technical notes, short communications and letters. Tutorial papers and special issues will also be published.