[Newly diagnosed non-acute promyelocytic leukemia combined with disseminated intravascular coagulation: a case report and literature review].

Abstract

Objective: Disseminated intravascular coagulation (DIC) is common in newly diagnosed acute promyelocytic leukemia (APL), with a high mortality rate. This case report focuses on a successful treatment of non-APL complicated with DIC, aiming to enhance clinical physicians' awareness and diagnostic skills in managing non-APL complicated by DIC. Methods: The diagnosis and treatment of a non-APL patient with DIC was detailed and related literature was reviewed. Results: With the help of early identification of DIC, chemotherapy and supportive treatment, the patient successfully recovered from DIC and achieved complete remission after induction therapy. He achieved long-term survival via subsequent hematopoietic stem cell transplantation. Conclusion: Non-APL patients with DIC are critically severe and early identification and timely intervention are necessary for them.