Factors associated with non-adherence to antiretroviral therapy among adolescents in Oshikoto Region, Namibia.

IF 1.2 Q2 MEDICINE, GENERAL & INTERNAL
Daniel O Ashipala, Tukwatha A Shuukwanyama, Abraham V Nghikevali
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引用次数: 0

Abstract

Background: In Namibia, the Omuthiya Antiretroviral Therapy (ART) Clinic has indicated that nine older adolescents (15-19 years) out of 125 adolescents active on ART have defaulted and become lost to care. This represents an 89% retention rate among older adolescents compared to a 97% retention rate for the adult population in the same facility. There is a lack of information on the extent of ART adherence among older adolescents, particularly in terms of viral suppression rates. This study aims to measure the level of adherence to ART treatment among adolescents enrolled at the Omuthiya ART Clinic in the Oshikoto Region, Namibia.

Methods: From November to December 2020, a cross-sectional study was conducted among 100 adolescents living with HIV (ALHIV) at the Omuthiya ART Clinic. Data were collected through structured questionnaires and analysed using descriptive statistics and logistic regression.

Results: The study found that 24% of adolescent patients on ART treated at the Omuthiya ART Clinic are non-adherent to treatment. A significant association found was between education level and adherence (p = 0.008), alcohol use and adherence (p = 0.022) and memory aids use and adherence (p  0.001).

Conclusion: Adolescents' adherence to ART at the Omuthiya ART Clinic is influenced by educational level, alcohol use, and memory aid use. Further research is needed to explore other potential factors influencing adherence.Contribution: These findings may be used to develop ongoing strategies and targeted interventions that prioritise a patient-centred care approach, recognising the autonomy of adolescents. In addition, they highlight the importance of a supportive family environment in managing HIV and improving ART adherence.

纳米比亚Oshikoto地区青少年不坚持抗逆转录病毒治疗的相关因素。
背景:在纳米比亚,Omuthiya抗逆转录病毒治疗(ART)诊所表明,在125名积极接受ART治疗的青少年中,有9名年龄较大的青少年(15-19岁)没有接受治疗,无法获得治疗。这表明,在同一设施中,年龄较大的青少年的保留率为89%,而成年人的保留率为97%。关于大龄青少年坚持抗逆转录病毒治疗的程度,特别是在病毒抑制率方面缺乏信息。本研究旨在衡量在纳米比亚Oshikoto地区Omuthiya ART诊所登记的青少年对ART治疗的坚持程度。方法:2020年11月至12月,在Omuthiya ART诊所对100名感染艾滋病毒(ALHIV)的青少年进行了横断面研究。通过结构化问卷收集数据,并使用描述性统计和逻辑回归进行分析。结果:研究发现,24%在Omuthiya ART诊所接受ART治疗的青少年患者没有坚持治疗。教育水平与依从性(p = 0.008)、酒精使用与依从性(p = 0.022)、记忆辅助工具使用与依从性(p = 0.001)之间存在显著关联。结论:青少年在Omuthiya ART诊所接受ART治疗的依从性受教育水平、酒精使用和记忆辅助剂使用的影响。需要进一步的研究来探索影响依从性的其他潜在因素。贡献:这些发现可用于制定持续的策略和有针对性的干预措施,优先考虑以患者为中心的护理方法,承认青少年的自主权。此外,它们强调了支持性家庭环境在管理艾滋病毒和改善抗逆转录病毒治疗依从性方面的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
South African Family Practice
South African Family Practice MEDICINE, GENERAL & INTERNAL-
CiteScore
1.50
自引率
20.00%
发文量
79
审稿时长
25 weeks
期刊介绍: South African Family Practice (SAFP) is a peer-reviewed scientific journal, which strives to provide primary care physicians and researchers with a broad range of scholarly work in the disciplines of Family Medicine, Primary Health Care, Rural Medicine, District Health and other related fields. SAFP publishes original research, clinical reviews, and pertinent commentary that advance the knowledge base of these disciplines. The content of SAFP is designed to reflect and support further development of the broad basis of these disciplines through original research and critical review of evidence in important clinical areas; as well as to provide practitioners with continuing professional development material.
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