J W Rohrbaugh, J M Stapleton, H W Frowein, B Adinoff, J L Varner, E A Lane, M J Eckardt, M Linnoila
{"title":"Acute effects of ethanol on motor performance and movement-related brain potentials.","authors":"J W Rohrbaugh, J M Stapleton, H W Frowein, B Adinoff, J L Varner, E A Lane, M J Eckardt, M Linnoila","doi":"10.1300/J251v07n03_09","DOIUrl":null,"url":null,"abstract":"<p><p>The acute effects of ethanol on skilled motor functions were examined in male social drinkers, under four doses ranging from 0 (placebo) to 1.05 g/kg lean body weight. The movement entailed a forewarned choice transitive motion of the arm and hand, aimed at a flanking target. Performance measures disclosed only small effects of ethanol on speed and accuracy of movement. The simultaneously-recorded movement-related brain potentials disclosed decreased involvement of frontal and posterior brain areas, suggesting that ethanol disrupted the planning and regulation of movement despite the overall preservation of reaction speed.</p>","PeriodicalId":77481,"journal":{"name":"Advances in alcohol & substance abuse","volume":"7 3-4","pages":"53-7"},"PeriodicalIF":0.0000,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1300/J251v07n03_09","citationCount":"8","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in alcohol & substance abuse","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1300/J251v07n03_09","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 8
Abstract
The acute effects of ethanol on skilled motor functions were examined in male social drinkers, under four doses ranging from 0 (placebo) to 1.05 g/kg lean body weight. The movement entailed a forewarned choice transitive motion of the arm and hand, aimed at a flanking target. Performance measures disclosed only small effects of ethanol on speed and accuracy of movement. The simultaneously-recorded movement-related brain potentials disclosed decreased involvement of frontal and posterior brain areas, suggesting that ethanol disrupted the planning and regulation of movement despite the overall preservation of reaction speed.