Factors associated with early return visits to the emergency department in patients with vaso-occlusive crisis.

IF 2.3 3区 医学 Q1 EMERGENCY MEDICINE
Mohammed Khalid Alageel, Hassan Mohammad Aloraini, Alanoud Mansour Alessa, Alanoud Binmethem, Ghada Alsaleh, Sarah Abdullah Almubrik, Abdulaziz Alalshaikh, Kholood K Altassan
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引用次数: 0

Abstract

Background and aim: One of the most common presentations of sickle cell disease (SCD) in the emergency department (ED) is acute severe pain episodes due to a vaso-occlusive crisis (VOC). Management of these episodes is primarily through intravenous pain control, but patients often return to the ED with the same complaint a few days after discharge. While some global studies have explored the risk factors for ED revisits due to VOC, the literature is lacking in the adult population, specifically in Saudi Arabia where SCD prevalence is high. The goal of this study is to measure the incidence of ED 72-hour early revisit (ERV) among SCD patients due to a VOC episode and to identify factors that might be associated with an ERV in this population. We conducted a retrospective cohort study using the electronic medical records, retrieving all patients who presented to the ED with a VOC from the period of 2017 to 2022.

Results: This study included 120 VOC visits. The percentage of 72-hour ERV to the ED among VOC patients was 39.2%, in which 91.5% received opioids, and 31.9% were admitted during the return visit. Return visitors' median age was 29, most of them were male. There was no statistically significant correlation found between the patients' 72-hour ERV to the ED and their age, gender, comorbidities, history of exchange transfusion, pain score, or dose of opiates received. Of the variables measured at the index visit only the direct bilirubin level, and time to first opioid dose was associated with 72-hour ERV with an OR of 1.08 (95%CI: 1.0 to 1.16, P = 0.022) and 0.99 (95%CI: 0.99 to 0.99, P = 0.012) respectively.

Conclusion: We found that 39.2% of VOC episodes discharged from the ED had an ERV. This rate is higher than what is reported internationally. Additionally, the lack of clear predictors for revisits raises doubts regarding the efficacy of the ED ''treat and release'' approach in this population.

Clinical trial number: Not applicable.

血管闭塞危像患者早期急诊回访的相关因素
背景和目的:镰状细胞病(SCD)在急诊科(ED)最常见的表现之一是由血管闭塞危象(VOC)引起的急性剧烈疼痛发作。这些发作的管理主要是通过静脉疼痛控制,但患者经常在出院后几天以同样的主诉回到急诊科。虽然一些全球研究已经探讨了VOC导致ED复诊的风险因素,但在成年人群中缺乏相关文献,特别是在SCD患病率高的沙特阿拉伯。本研究的目的是测量由于VOC发作导致的SCD患者72小时早期重访(ERV)的发生率,并确定该人群中可能与ERV相关的因素。我们使用电子病历进行了一项回顾性队列研究,检索了2017年至2022年期间所有因VOC而就诊于急诊科的患者。结果:本研究包括120次VOC访问。在VOC患者中,72小时ERV到ED的比例为39.2%,其中91.5%使用阿片类药物,31.9%在复诊时入院。回访者年龄中位数为29岁,男性居多。患者到ED的72小时ERV与患者的年龄、性别、合并症、换血史、疼痛评分或接受的阿片类药物剂量之间没有统计学上的显著相关性。在指标访视测量的变量中,仅胆红素直接水平和阿片类药物首次给药时间与72小时ERV相关,OR分别为1.08 (95%CI: 1.0 ~ 1.16, P = 0.022)和0.99 (95%CI: 0.99 ~ 0.99, P = 0.012)。结论:我们发现39.2%的急诊科VOC发作有ERV。这个比率比国际上报道的要高。此外,缺乏明确的复诊预测因素,这引起了人们对ED“治疗和释放”方法在这一人群中的有效性的怀疑。临床试验号:不适用。
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来源期刊
BMC Emergency Medicine
BMC Emergency Medicine Medicine-Emergency Medicine
CiteScore
3.50
自引率
8.00%
发文量
178
审稿时长
29 weeks
期刊介绍: BMC Emergency Medicine is an open access, peer-reviewed journal that considers articles on all urgent and emergency aspects of medicine, in both practice and basic research. In addition, the journal covers aspects of disaster medicine and medicine in special locations, such as conflict areas and military medicine, together with articles concerning healthcare services in the emergency departments.
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