Association of Average Cyst Diameter Versus Single Maximum Diameter of Pancreatic Cysts to Cyst Volume and Impact on Screening Guideline Classification

IF 4 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of the American College of Radiology Pub Date : 2025-03-01 DOI:10.1016/j.jacr.2024.12.005

Sara Babapour MD , Abraham F. Bezuidenhout MD , Miriel Handler MD , Clarissa Lee , Alexander Brook PhD , Leo L. Tsai MD, PhD

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引用次数: 0

Abstract

Objective

To compare the association of single maximum diameter and average cyst diameter of pancreatic cysts measured on magnetic resonance cholangiopancreatography (MRCP) with segmented cyst volume and secondarily evaluate the effect of average cyst diameter on screening guideline classification.

Methods

Consecutive patients with pancreatic cysts < 3 cm on MRCP in 2017 were retrospectively identified. The single maximum diameter and perpendicular short axis diameter of pancreatic cysts obtained on coronal MRCP were measured and their average was taken to determine average cyst diameter. Calculated volume approximations based on single maximum diameter and average cyst diameter were compared with segmented cyst volume. Subsequently, patients were classified based on average cyst diameter versus single maximum diameter according to a currently used screening guideline. Intraclass correlation was used to assess interobserver agreement. Williams’s test was used to compare between-group correlation coefficients.

Results

The mean value of single maximum diameters and average cyst diameter of the 86 included cysts were 15.4 ± 7.3 mm and 12.6 ± 6.1 mm, respectively. The mean volume of segmented cysts was 1,521 ± 1,983 mm³. Interreader agreement for measurement of cyst diameters was excellent (r = 0.99). The volume calculated based on the average cyst diameter correlated better to segmented cyst volume (r = 0.88) than single maximum diameter (r = 0.73, P < .0001). Of 86 patients, 24 (28%) were classified to a less stringent follow-up strategy by using average cyst diameter.

Discussion

The average cyst diameter more accurately reflects the segmented cyst volume than a single maximum diameter. Utilization of average cyst diameter in existing screening guidelines reclassified 28% of patients into lower-risk screening groups, which would reduce subsequent surveillance imaging overall.

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来源期刊

Journal of the American College of Radiology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

6.30

自引率

8.90%

发文量

312

审稿时长

34 days

期刊介绍： The official journal of the American College of Radiology, JACR informs its readers of timely, pertinent, and important topics affecting the practice of diagnostic radiologists, interventional radiologists, medical physicists, and radiation oncologists. In so doing, JACR improves their practices and helps optimize their role in the health care system. By providing a forum for informative, well-written articles on health policy, clinical practice, practice management, data science, and education, JACR engages readers in a dialogue that ultimately benefits patient care.