A case report on a late diagnosis of pilocytic astrocytoma in a Dandy–Walker complex

Juan Sebastián Solis-Mata , Fernando Castro-Soto , José Alfonso Alvarez-Castro , Sonia Iliana Mejía-Pérez
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Abstract

Dandy–Walker malformation (DWM) and pilocytic astrocytoma are entities that manifest themselves at an early age. DWM is a cerebella type associated with several anatomical changes. Very few cases of concomitant occurrence of DWM and pilocytic astrocytoma have been reported on the literature. Male 20 years old, clinical history of 6 months of evolution with nausea, dizziness, headache, photophobia, phonofobia, vomiting, walking laterality, diplopia, tonic–clonic seizures, nystagmus, dysmetria, and dysdiadochokinesia. Cranial tomography was performed, reporting hydrocephaly data with significant dilation of the IV ventricle and the presence of a tumor lesion in the posterior fossa of the right cerebellar hemisphere. Pediatric tumors that manifest in adulthood are rare, with signs such as intracranial hypertension and compress the cranial nerves. The prognosis will be determined by the accompanying abnormalities as well as the effectiveness of the appropriate treatment.
丹迪-沃克畸形(Dandy-Walker malformation,DWM)和朝粒细胞性星形细胞瘤都是幼年时就会出现的疾病。丹迪-沃克畸形是一种伴有多种解剖学改变的小脑畸形。文献中很少有 DWM 和朝粒细胞星形细胞瘤同时出现的病例。患者男性,20 岁,临床病史 6 个月,伴有恶心、头晕、头痛、畏光、畏声、呕吐、偏侧方行走、复视、强直阵挛发作、眼球震颤、构音障碍和运动障碍。进行了头颅断层扫描,结果显示颅底积水,第四脑室明显扩张,右侧小脑半球后窝存在肿瘤病灶。小儿肿瘤在成年后表现为颅内高压和压迫颅神经等症状的情况非常罕见。预后将取决于伴随的异常情况以及适当治疗的效果。
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