Strawberry gingivitis as an initial presentation of granulomatosis with polyangiitis in an older adult

IF 2 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Gerodontology Pub Date : 2025-02-28 DOI:10.1111/ger.12797

José Alcides Almeida de Arruda, Victor Zanetti Drumond, Maria Danielle Fontes, José Victor Lemos Ventura, Jefferson R. Tenório, Bruno Augusto Benevenuto de Andrade

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Abstract

Objective

To describe a rare case of granulomatosis with polyangiitis (GPA) in an older adult in light of the existing literature.

Background

GPA is a potentially life-threatening multisystem necrotising vasculitis, characterised by a spectrum of oral mucosal lesions that present diagnostic challenges.

Materials and Methods

A 76-year-old female patient presented with asymptomatic granular and haemorrhage swelling (“strawberry” gingivitis) affecting the upper and lower anterior and posterior gingivae. Cytoplasmic antineutrophil cytoplasmic antibody (ANCA) was positive. Concurrent kidney lesions were diagnosed.

Results

Histopathological examination revealed a pseudoepitheliomatous proliferation with perivascular inflammation and a dense eosinophilic infiltrate. After a 5-year follow-up, the patient showed no signs of recurrence. A literature review performed using PubMed, Web of Science and Scopus identified 22 documented cases of GPA-related oral lesions in older adults, with equal sex distribution and 63.6% occurring in the seventh decade of life.

Conclusion

Early recognition and diagnosis of “strawberry” gingivitis in older adults with GPA are crucial, as these oral manifestations may be the initial presentation of the disease.

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来源期刊

Gerodontology 医学-老年医学

CiteScore

4.10

自引率

10.00%

发文量

审稿时长

3-6 weeks

期刊介绍： The ultimate aim of Gerodontology is to improve the quality of life and oral health of older people. The boundaries of most conventional dental specialties must be repeatedly crossed to provide optimal dental care for older people. In addition, management of other health problems impacts on dental care and clinicians need knowledge in these numerous overlapping areas. Bringing together these diverse topics within one journal serves clinicians who are seeking to read and to publish papers across a broad spectrum of specialties. This journal provides the juxtaposition of papers from traditional specialties but which share this patient-centred interest, providing a synergy that serves progress in the subject of gerodontology.