Zika virus: advancing a priority research agenda for preparedness and response

IF 36.4 1区医学 Q1 INFECTIOUS DISEASES

Lancet Infectious Diseases Pub Date : 2025-02-27 DOI:10.1016/s1473-3099(24)00794-1

Eve M Lackritz, Lee-Ching Ng, Ernesto T A Marques, Ingrid B Rabe, Nigel Bourne, J Erin Staples, Jairo A Méndez-Rico, Eva Harris, Aaron C Brault, Albert I Ko, David W C Beasley, Tabitha Leighton, Annelies Wilder-Smith, Julia T Ostrowsky, Angela J Mehr, Angela K Ulrich, Raman Velayudhan, Josephine P Golding, Petra C Fay, Ana Cehovin, Jurai Wongsawat

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引用次数: 0

Abstract

The 2015–16 Zika virus epidemic emerged in the Americas and rapidly spread throughout the region and beyond, showing the epidemic potential of this mosquito-borne Orthoflavivirus and its capacity to cause severe congenital malformations and neurological sequelae. WHO declared the Zika virus epidemic a public health emergency of international concern in 2016. Despite this declaration, there are no licensed Zika virus vaccines, therapeutics, or diagnostic tests appropriate for routine antenatal screening. To address this absence of essential tools to detect and mitigate the threat of future Zika virus outbreaks, a group of global experts developed a priority agenda for Zika virus research and development. This Series paper summarises crucial challenges and knowledge gaps and outlines a comprehensive strategy to advance research, surveillance, global capacity, policy, and investment for Zika virus preparedness and response.

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寨卡病毒：推进防范和应对的优先研究议程

2015-16年寨卡病毒流行出现在美洲，并迅速蔓延到整个地区及其他地区，显示出这种蚊媒正黄病毒的流行潜力及其导致严重先天性畸形和神经系统后遗症的能力。2016年，世卫组织宣布寨卡病毒疫情为国际关注的突发公共卫生事件。尽管有上述声明，但目前还没有获得许可的寨卡病毒疫苗、治疗药物或适合常规产前筛查的诊断检测。为了解决缺乏发现和减轻未来寨卡病毒疫情威胁的基本工具的问题，一组全球专家制定了寨卡病毒研究和开发的优先议程。本系列文件总结了重大挑战和知识差距，并概述了一项全面战略，以推进寨卡病毒防范和应对方面的研究、监测、全球能力、政策和投资。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Lancet Infectious Diseases 医学-传染病学

CiteScore

60.90

自引率

0.70%

发文量

1064

审稿时长

6-12 weeks

期刊介绍： The Lancet Infectious Diseases was launched in August, 2001, and is a lively monthly journal of original research, review, opinion, and news covering international issues relevant to clinical infectious diseases specialists worldwide.The infectious diseases journal aims to be a world-leading publication, featuring original research that advocates change or sheds light on clinical practices related to infectious diseases. The journal prioritizes articles with the potential to impact clinical practice or influence perspectives. Content covers a wide range of topics, including anti-infective therapy and immunization, bacterial, viral, fungal, and parasitic infections, emerging infectious diseases, HIV/AIDS, malaria, tuberculosis, mycobacterial infections, infection control, infectious diseases epidemiology, neglected tropical diseases, and travel medicine. Informative reviews on any subject linked to infectious diseases and human health are also welcomed.