Osteonecrosis following Steroid Therapy in COVID-19 Patients: An Outlook on the Emerging Problem.

Jaiben George, Deepak Gautam, Maria Rose Dominic, Rajesh Malhotra
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引用次数: 0

Abstract

Steroids are used in management of coronavirus disease 2019 (COVID-19) patients with severe illness and their use has been demonstrated to decrease mortality. Although life-saving, steroids are well documented as risk factors for osteonecrosis. Osteonecrosis of the hip can be debilitating and surgery may be required to improve the quality of life. With the increasing number of COVID-19 cases, osteonecrosis of the hip and other joints resulting from steroid use is expected to show a sharp rise in the coming years. In this review we discuss the association between steroids and osteonecrosis, indications for steroid therapy in COVID-19 patients, and incidence, diagnosis, and treatment of osteonecrosis secondary to steroids in COVID-19.

COVID-19患者类固醇治疗后骨坏死:对新出现问题的展望
类固醇用于治疗2019冠状病毒病(COVID-19)重症患者,并已被证明可降低死亡率。虽然可以挽救生命,但类固醇是骨坏死的危险因素。髋关节骨坏死会使人衰弱,可能需要手术来改善生活质量。随着COVID-19病例数量的增加,预计未来几年因使用类固醇导致的髋关节和其他关节骨坏死将急剧增加。在这篇综述中,我们讨论了类固醇与骨坏死之间的关系,COVID-19患者类固醇治疗的适应症,以及COVID-19中类固醇继发性骨坏死的发病率、诊断和治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
2.90
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