Rheumatological diseases in patients with autoimmune hepatitis in a fourth level hospital in Bogotá between 2013 and 2023

Reumatologia clinica Pub Date : 2025-02-01 DOI:10.1016/j.reumae.2025.501812

Juan Sebastián Almánzar Cortés , Cathalina Vergara Cabra , María Paula Uchima-Vera , Gerardo Quintana , Fernando Sierra

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Abstract

Introduction

Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease with low prevalence worldwide. The coexistence of this entity with rheumatic diseases has been evaluated in multiple studies and is highly variable. The objective of this study is to identify the frequency of coexistence of rheumatic diseases and autoimmune hepatitis in adults who have been treated for 10 years in a fourth-level hospital in Bogota, Colombia.

Materials and methods

Analytical, observational, cross-sectional study in a single center that included patients over 18 years of age of both sexes with a diagnosis of AIH by simplified score ≥7 points, with a medical history registered at the Fundacion Santa Fe de Bogota in Bogota, Colombia between January 2013 and December 2023.

Results

A total of 66 patients met inclusion criteria. 36.4% of patients had a concomitant autoimmune disease, with Sjögren's syndrome, systemic lupus erythematosus and autoimmune thyroid disease being the most prevalent.

Conclusion

The frequency of coexistence of autoimmune hepatitis with rheumatic diseases in adult patients is 36.4% for the cohort studied, which is within the range of what has already been reported globally, where a prevalence of 14 to 44% has been described.

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2013年至2023年波哥大一家四级医院自身免疫性肝炎患者的风湿病

自身免疫性肝炎（AIH）是一种全球低患病率的慢性炎症性肝病。该实体与风湿病的共存已在多项研究中进行了评估，并且是高度可变的。本研究的目的是确定在哥伦比亚波哥大一家四级医院治疗10年的成人中风湿性疾病和自身免疫性肝炎共存的频率。材料和方法：在单中心进行分析性、观察性、横断面研究，纳入年龄在18岁以上、简化评分≥7分诊断为AIH的患者，病史于2013年1月至2023年12月在哥伦比亚波哥大的Fundacion Santa Fe de Bogota登记。结果：66例患者符合纳入标准。36.4%的患者伴有自身免疫性疾病，其中Sjögren综合征、系统性红斑狼疮和自身免疫性甲状腺疾病最为常见。结论：在研究的队列中，自身免疫性肝炎与风湿性疾病在成人患者中共存的频率为36.4%，这与全球已报道的14%至44%的患病率范围一致。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Reumatologia clinica

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