{"title":"Clival metastasis presenting with oculomotor nerve palsy in a patient with a prior history of breast cancer.","authors":"E Visser, K Elmusharaf, A Ryan, M O'Connor","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Presentation: </strong>A 77-year-old female patient presented with a short history of left sided ptosis, temporal headache, retro-orbital pain and diplopia having had a history of Stage IIA (T1mfN1) right breast cancer two years previously.</p><p><strong>Diagnosis: </strong>CT-brain imaging documented an enhancing clival lesion and no other sites of disease. Histopathology via endoscopic transsphenoidal craniotomy debulking confirmed metastatic breast cancer.</p><p><strong>Treatment: </strong>Transsphenoidal craniotomy debulking resulted in symptomatic relief and resolved the ptosis and diplopia. She received stereotactic radiosurgery (SRS). She was commenced on bisphosphonate and systemic chemotherapy.</p><p><strong>Discussion: </strong>Clival metastases have been reported in association with a myriad of cancers; however, there are limited cases of solitary clival metastasis in the literature, none of which have presented with an oculomotor nerve palsy.</p>","PeriodicalId":14713,"journal":{"name":"Irish medical journal","volume":"118 2","pages":"24"},"PeriodicalIF":0.0000,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Irish medical journal","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Presentation: A 77-year-old female patient presented with a short history of left sided ptosis, temporal headache, retro-orbital pain and diplopia having had a history of Stage IIA (T1mfN1) right breast cancer two years previously.
Diagnosis: CT-brain imaging documented an enhancing clival lesion and no other sites of disease. Histopathology via endoscopic transsphenoidal craniotomy debulking confirmed metastatic breast cancer.
Treatment: Transsphenoidal craniotomy debulking resulted in symptomatic relief and resolved the ptosis and diplopia. She received stereotactic radiosurgery (SRS). She was commenced on bisphosphonate and systemic chemotherapy.
Discussion: Clival metastases have been reported in association with a myriad of cancers; however, there are limited cases of solitary clival metastasis in the literature, none of which have presented with an oculomotor nerve palsy.
期刊介绍：
Since its inception in 1867, the Journal of the Medical Association of Ireland and now in its present format, the Irish Medical Journal, has provided the medical community in Ireland with an invaluable service. As one of the leading biomedical publications in Ireland, it has sought to continue the education of medical students and postgraduates through scientific research, review articles and updates on contemporary clinical practices while providing an ongoing forum for medical debate. A measure of our stature is that we are listed in the Index Medicus and issued annually with a citation factor from the Institute for Scientific Information.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
