[Application Research of mDIXON-Quant Quantitative T2* Values and FF Values in Cervical Intervertebral Disc Degeneration].

Q4 Medicine

中国医疗器械杂志 Pub Date : 2025-01-30 DOI:10.12455/j.issn.1671-7104.240348

Peng Liu, Meichen Niu, Hong Liu

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引用次数: 0

Abstract

Objective: To investigate the clinical value of MRI modified water-lipid separation technique (mDIXON-Quant) in terms of T2* values and fat fraction (FF) values for evaluating the degree of cervical intervertebral disc degeneration.

Methods: A total of 118 patients who underwent routine MRI of the cervical vertebra and the mDIXON-Quant examination in Fuyang People's Hospital from March 2019 to January 2024 were collected. The T2* values of C2/3 to C6/7 intervertebral discs and FF values of the upper and lower vertebral bodies were measured. Cervical intervertebral disc degeneration was graded according to the Pfirrmann criteria. The T2* values and FF values of different patients were compared with the Pfirrmann grades, and the correlation between T2* values, FF values, and Pfirrmann grades was analyzed by Spearman correlation.

Results: The T2* values of cervical intervertebral discs in grades I, II, III, IV, and V all showed a decreasing trend ( P＜0.05). The decreasing order of FF values in the upper cervical vertebra was IV, V, III, II, and I ( F=93.28, P＜0.05), and the decreasing order of FF values in the lower cervical vertebra was IV, III, V, II, and I ( F=112.037, P＜0.05). Spearman correlation analysis showed that the T2* values of cervical intervertebral discs were negatively correlated with the Pfirrmann grades ( P＜0.05), and the FF values of the upper and lower vertebrae were positively correlated with the Pfirrmann grades ( P＜0.05).

Conclusion: The mDIXON-Quant technique can be used to quantify the T2* values and FF values of cervical intervertebral disc degeneration and plays an important role in accurate clinical diagnosis and evaluation of treatment effects.

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[mdixon -定量T2*值和FF值在椎间盘退变中的应用研究]。

目的：探讨MRI改良水脂分离技术（mDIXON-Quant）在T2*值和脂肪分数（FF）值方面评价颈椎间盘退变程度的临床价值。方法：收集2019年3月至2024年1月阜阳市人民医院行颈椎常规MRI检查和mdixon -定量检查的患者118例。测量C2/3 ~ C6/7椎间盘T2*值及上下椎体FF值。根据Pfirrmann标准对颈椎间盘退变进行分级。将不同患者的T2*值、FF值与Pfirrmann分级进行比较，采用Spearman相关分析T2*值、FF值与Pfirrmann分级之间的相关性。结果：I级、II级、III级、IV级、V级颈椎间盘T2*值均呈下降趋势（P<0.05）。上颈椎FF值下降顺序为IV、V、III、II、I (F=93.28， P<0.05)，下颈椎FF值下降顺序为IV、III、V、II、I （F=112.037， P<0.05）。Spearman相关分析显示，颈椎间盘T2*值与Pfirrmann分级呈负相关（P<0.05），上下椎体FF值与Pfirrmann分级呈正相关（P<0.05）。结论：mDIXON-Quant技术可量化颈椎间盘退变的T2*值和FF值，对临床准确诊断和评价治疗效果具有重要作用。

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来源期刊

中国医疗器械杂志 Medicine-Medicine (all)

CiteScore

0.40

自引率

0.00%

发文量

8086

期刊介绍： Chinese Journal of Medical Instrumentation mainly reports on the development, progress, research and development, production, clinical application, management, and maintenance of medical devices and biomedical engineering. Its aim is to promote the exchange of information on medical devices and biomedical engineering in China and turn the journal into a high-quality academic journal that leads academic directions and advocates academic debates.