The Dural Deviation Ratio: A Novel Indicator for Preoperative Differentiation of Intradural Extension in Spinal Dumbbell Tumors Schwannomas Using Axial T2-weighted MRI.

IF 4.9 1区医学 Q1 CLINICAL NEUROLOGY

Spine Journal Pub Date : 2025-02-22 DOI:10.1016/j.spinee.2025.02.003

Rei Kimura, Ko Hashimoto, Kohei Takahashi, Takahiro Onoki, Kenichiro Yahata, Toshimi Aizawa

{"title":"The Dural Deviation Ratio: A Novel Indicator for Preoperative Differentiation of Intradural Extension in Spinal Dumbbell Tumors Schwannomas Using Axial T2-weighted MRI.","authors":"Rei Kimura, Ko Hashimoto, Kohei Takahashi, Takahiro Onoki, Kenichiro Yahata, Toshimi Aizawa","doi":"10.1016/j.spinee.2025.02.003","DOIUrl":null,"url":null,"abstract":"Objective: This study investigates the potential of using dural deviation in axial T2-weighted MRI to differentiate between Eden type-2 and type-3 spinal dumbbell schwannomas preoperatively.Methods: A retrospective analysis of 43 patients with spinal dumbbell Schwannomas was conducted. Tumors were classified into Eden type-2 or type-3 based on the need for dural incision during surgery. The dural deviation ratio (D-ratio) was measured using axial T2-weighted MRI. Statistical significance and diagnostic accuracy were assessed with Mann-Whitney U test and receiver operating characteristic (ROC) analysis. The authors declare no conflicts of interest and no funding sources for this study.Results: The D-ratio was significantly higher in type-2 tumors (median: 0.904) than in type-3 tumors (median: 0.585) (p < 0.001). ROC analysis showed an AUC of 0.950, with a cut-off value of 0.746, 92.4% sensitivity, and 91.2% specificity.Conclusions: The D-ratio is a reliable indicator for distinguishing between type-2 and type-3 Schwannomas, with a cut-off value of 0.746.","PeriodicalId":49484,"journal":{"name":"Spine Journal","volume":" ","pages":""},"PeriodicalIF":4.9000,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Spine Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.spinee.2025.02.003","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: This study investigates the potential of using dural deviation in axial T2-weighted MRI to differentiate between Eden type-2 and type-3 spinal dumbbell schwannomas preoperatively.

Methods: A retrospective analysis of 43 patients with spinal dumbbell Schwannomas was conducted. Tumors were classified into Eden type-2 or type-3 based on the need for dural incision during surgery. The dural deviation ratio (D-ratio) was measured using axial T2-weighted MRI. Statistical significance and diagnostic accuracy were assessed with Mann-Whitney U test and receiver operating characteristic (ROC) analysis. The authors declare no conflicts of interest and no funding sources for this study.

Results: The D-ratio was significantly higher in type-2 tumors (median: 0.904) than in type-3 tumors (median: 0.585) (p < 0.001). ROC analysis showed an AUC of 0.950, with a cut-off value of 0.746, 92.4% sensitivity, and 91.2% specificity.

Conclusions: The D-ratio is a reliable indicator for distinguishing between type-2 and type-3 Schwannomas, with a cut-off value of 0.746.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Spine Journal 医学-临床神经学

CiteScore

8.20

自引率

6.70%

发文量

680

审稿时长

13.1 weeks

期刊介绍： The Spine Journal, the official journal of the North American Spine Society, is an international and multidisciplinary journal that publishes original, peer-reviewed articles on research and treatment related to the spine and spine care, including basic science and clinical investigations. It is a condition of publication that manuscripts submitted to The Spine Journal have not been published, and will not be simultaneously submitted or published elsewhere. The Spine Journal also publishes major reviews of specific topics by acknowledged authorities, technical notes, teaching editorials, and other special features, Letters to the Editor-in-Chief are encouraged.