mSphere of Influence: Rapid evolution of pathogenesis and drug resistance in human pathogenic fungi.

IF 3.7 2区生物学 Q2 MICROBIOLOGY

mSphere Pub Date : 2025-03-25 Epub Date: 2025-02-25 DOI:10.1128/msphere.00570-24

Pengjie Hu

引用次数: 0

Abstract

Pengjie Hu works in the field of fungal pathogenesis, drug resistance, and evolution. In this mSphere of Influence article, he reflects on how three works, "Transposon mobilization in the human fungal pathogen Cryptococcus is mutagenic during infection and promotes drug resistance in vitro" and "Genome-wide analysis of heat stress-stimulated transposon mobility in the human fungal pathogen Cryptococcus deneoformans" by Gusa et al. and "Rapid evolution of an adaptive multicellular morphology of Candida auris during systemic infection" by Bing et al. have impacted his work on the evolution of virulence, resistance, and adaptation in human fungal pathogens.

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影响范围：人类致病真菌的发病机制和耐药性的快速演变。

胡鹏杰从事真菌发病机制、耐药和进化研究。在这篇影响范围的文章中，他反思了三种工作方式，“人类真菌病原体隐球菌的转座子动员在感染过程中具有诱变性，并在体外促进耐药性”、Gusa等人的“热应激刺激下人类真菌病原体隐球菌转座子迁移的全基因组分析”和Bing等人的“假丝酵母在全身感染过程中适应性多细胞形态的快速进化”影响了他在毒力、耐药性、以及人类真菌病原体的适应性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

mSphere Immunology and Microbiology-Microbiology

CiteScore

8.50

自引率

2.10%

发文量

192

审稿时长

11 weeks

期刊介绍： mSphere™ is a multi-disciplinary open-access journal that will focus on rapid publication of fundamental contributions to our understanding of microbiology. Its scope will reflect the immense range of fields within the microbial sciences, creating new opportunities for researchers to share findings that are transforming our understanding of human health and disease, ecosystems, neuroscience, agriculture, energy production, climate change, evolution, biogeochemical cycling, and food and drug production. Submissions will be encouraged of all high-quality work that makes fundamental contributions to our understanding of microbiology. mSphere™ will provide streamlined decisions, while carrying on ASM''s tradition for rigorous peer review.