Evaluating the Effect of Body Mass Index on Procalcitonin Level in Patients with Pneumonia: A Retrospective Cross-Sectional Study.

IF 1.8 Q3 RESPIRATORY SYSTEM

Advances in respiratory medicine Pub Date : 2025-01-26 DOI:10.3390/arm93010001

Mohammad Z Khrais, J Curran Henson, Jake Smith, Nikhil Meena

{"title":"Evaluating the Effect of Body Mass Index on Procalcitonin Level in Patients with Pneumonia: A Retrospective Cross-Sectional Study.","authors":"Mohammad Z Khrais, J Curran Henson, Jake Smith, Nikhil Meena","doi":"10.3390/arm93010001","DOIUrl":null,"url":null,"abstract":"Procalcitonin (PCT) is commonly used to evaluate the etiology and severity of pneumonia. PCT has been shown to be elevated at baseline in patients with obesity. The aim of this study is to determine if body mass index (BMI) has an influence on admission PCT level in patients admitted to the hospital with a diagnosis of pneumonia. We conducted a retrospective cohort study that encompassed patient visits to a tertiary care center from 2014 until September 2023. A total of 18,652 patients presented to the emergency department with a diagnosis of pneumonia. A total of 3659 were admitted to the floor, and 2246 were admitted to the MICU. Patients were grouped based on admission BMI into five categories. The Kruskal-Wallis test performed on patients admitted to the floor revealed a statistically significant difference in PCT levels among groups of different BMIs (H = 34.97, df = 4, p < 0.001). In patients admitted to the MICU, the Kruskal-Wallis test revealed a significant difference in PCT levels among groups of different BMIs (H = 32.92, df = 4, p < 0.001). BMI has a statistically significant effect on PCT in patients admitted to the hospital with pneumonia. Patients with higher BMI may exhibit less robust PCT levels, which may impact management decisions.","PeriodicalId":7391,"journal":{"name":"Advances in respiratory medicine","volume":"93 1","pages":""},"PeriodicalIF":1.8000,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11851394/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in respiratory medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/arm93010001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}

引用次数: 0

Abstract

Procalcitonin (PCT) is commonly used to evaluate the etiology and severity of pneumonia. PCT has been shown to be elevated at baseline in patients with obesity. The aim of this study is to determine if body mass index (BMI) has an influence on admission PCT level in patients admitted to the hospital with a diagnosis of pneumonia. We conducted a retrospective cohort study that encompassed patient visits to a tertiary care center from 2014 until September 2023. A total of 18,652 patients presented to the emergency department with a diagnosis of pneumonia. A total of 3659 were admitted to the floor, and 2246 were admitted to the MICU. Patients were grouped based on admission BMI into five categories. The Kruskal-Wallis test performed on patients admitted to the floor revealed a statistically significant difference in PCT levels among groups of different BMIs (H = 34.97, df = 4, p < 0.001). In patients admitted to the MICU, the Kruskal-Wallis test revealed a significant difference in PCT levels among groups of different BMIs (H = 32.92, df = 4, p < 0.001). BMI has a statistically significant effect on PCT in patients admitted to the hospital with pneumonia. Patients with higher BMI may exhibit less robust PCT levels, which may impact management decisions.

查看原文本刊更多论文

评价体重指数对肺炎患者降钙素原水平的影响：一项回顾性横断面研究。

降钙素原（PCT）通常用于评估肺炎的病因和严重程度。肥胖患者的PCT已被证明在基线时升高。本研究的目的是确定体重指数（BMI）是否对诊断为肺炎入院患者的入院PCT水平有影响。我们进行了一项回顾性队列研究，包括2014年至2023年9月期间到三级医疗中心就诊的患者。共有18,652名诊断为肺炎的患者就诊于急诊科。总共有3659人被录取到一楼，2246人被录取到特派团。患者根据入院BMI分为五类。对住院患者进行的Kruskal-Wallis检验显示，不同bmi组间PCT水平差异有统计学意义（H = 34.97, df = 4, p < 0.001）。在入住MICU的患者中，Kruskal-Wallis检验显示不同bmi组间PCT水平有显著差异（H = 32.92, df = 4, p < 0.001）。BMI对住院肺炎患者PCT的影响有统计学意义。BMI较高的患者可能表现出较弱的PCT水平，这可能影响管理决策。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Advances in respiratory medicine RESPIRATORY SYSTEM-

CiteScore

2.60

自引率

0.00%

发文量

期刊介绍： "Advances in Respiratory Medicine" is a new international title for "Pneumonologia i Alergologia Polska", edited bimonthly and addressed to respiratory professionals. The Journal contains peer-reviewed original research papers, short communications, case-reports, recommendations of the Polish Respiratory Society concerning the diagnosis and treatment of lung diseases, editorials, postgraduate education articles, letters and book reviews in the field of pneumonology, allergology, oncology, immunology and infectious diseases. "Advances in Respiratory Medicine" is an open access, official journal of Polish Society of Lung Diseases, Polish Society of Allergology and National Research Institute of Tuberculosis and Lung Diseases.