Eye yoga for glaucoma: recovery of vascular dysregulation and visual field function-a randomized controlled trial.

Abstract

Purpose: Because stress can aggravate vascular dysregulation (VD) in primary open-angle glaucoma (POAG), stress reduction by eye yoga (EY) was studied if this predictive, preventive, and personalized medical (3PM) approach could help normalize intraocular pressure (IOP), retinal vessel dynamics, and visual fields (VF).

Patients and methods: POAG patients were randomized to an EY (n = 15) or control group (n = 12). EY was practiced daily for 1 h for 1 month at home using an iPod-audio guide while control patients read relaxing books daily.

Results: After intervention, EY patients, but not controls, showed a 6.4% IOP reduction (p = 0.027) and had significant VF improvements (p < 0.001). After EY, pattern deviation recovered in VF regions where small microvessels showed reduced vasoconstriction (artery: p = 0.012; vein: p = 0.042) and improved mean artery diameter recovered significantly (p = 0.015). When pooling data of both groups, recovered VF regions, but not non-recovered fields, showed significantly larger arterial diameter gains (2.4 [- 0.3-5.3] MU) with no adverse events.

Conclusions and 3pm recommendations: Because EY reduces vasoconstriction and improves VF function in POAG, we propose the "eye ball retraction theory," whereby ocular muscle tension is induced by mental stress which is a contributing mechanism, or even the key mechanism, of POAG. Reducing stress by relaxation is therefore a remedy for it improves blood flow as the fundamental mechanism of vision recovery and restoration. VD reduction is therefore a valuable therapeutic target for glaucoma care and eye yoga home exercises are a safe and effective complementary 3PM method of POAG care.

Supplementary information: The online version contains supplementary material available at 10.1007/s13167-024-00389-x.