The Updated Genome Warehouse: Enhancing Data Value, Security, and Usability to Address Data Expansion.

Genomics, proteomics & bioinformatics Pub Date : 2025-02-20 DOI:10.1093/gpbjnl/qzaf010

Yingke Ma, Xuetong Zhao, Yaokai Jia, Zhenxian Han, Caixia Yu, Zhuojing Fan, Zhang Zhang, Jingfa Xiao, Wenming Zhao, Yiming Bao, Meili Chen

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Abstract

The Genome Warehouse (GWH), accessible at https://ngdc.cncb.ac.cn/gwh, is an extensively utilized public repository dedicated to the deposition, management and sharing of genome assembly sequences, annotations, and metadata. This paper highlights noteworthy enhancements to the GWH since the 2021 version, emphasizing substantial advancements in web interfaces for data submission, database functionality updates, and resource integration. Key updates include the reannotation of released prokaryotic genomes, mirroring of genome resources from National Center for Biotechnology Information (NCBI) GenBank and Reference Sequence Database (RefSeq), integration of Poxviridae sequences, implementation of an online batch submission system, enhancements to the quality control system, advanced search capabilities, and the introduction of a controlled-access mechanism for human genome data. These improvements collectively augment the ease and security of data submission and access as well as genome data value, thereby fostering heightened convenience and utility for researchers in the genomics field.

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更新的基因组仓库：增强数据价值、安全性和可用性以应对数据扩展。

基因组仓库（GWH）可通过 https://ngdc.cncb.ac.cn/gwh 访问，它是一个广泛使用的公共存储库，专门用于存放、管理和共享基因组组装序列、注释和元数据。本文重点介绍了 GWH 自 2021 年版本以来值得关注的改进，强调了在数据提交网络接口、数据库功能更新和资源整合方面的重大进展。主要更新包括对已发布的原核生物基因组进行重新注释、镜像美国国家生物技术信息中心（NCBI）GenBank 和参考序列数据库（RefSeq）的基因组资源、整合 Poxviridae 序列、实施在线批量提交系统、增强质量控制系统、高级搜索功能以及引入人类基因组数据受控访问机制。这些改进共同提高了数据提交和访问的便捷性和安全性以及基因组数据的价值，从而为基因组学领域的研究人员提供了更大的便利和效用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Genomics, proteomics & bioinformatics

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