Microbial Profiles of Osteoradionecrosis Lesions: A Case Report With Implications for Implant-Related Infections.

Aljomar José Vechiato-Filho, Maria Cláudia Cuzzullin, Ana Leticia Mores, Thais Bianca Brandão, Valentim Adelino Ricardo Barão, Alan Roger Santo-Silva, Ana Carolina Prado Ribeiro-Silva, João Gabriel Silva Souza
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Abstract

Osteoradionecrosis (ORN) lesion, a significant late toxicity associated with radiotherapy for head and neck cancer, may serve as a suitable habitat for the accumulation of important oral pathogens, which may increase the risk of implant-related infections and rehabilitation failures in patients with dental implants. This clinical report assessed the microbial profile on the ORN lesion, the dental implant located adjacent to the lesion and in the contralateral area, and the saliva of a patient attended dental service from a public cancer institute. The patient was subjected to surgical debridement of ORN but it persisted. This suggests that ORN lesions may serve as microbial reservoirs, posing a significant risk factor for biofilm-related oral infections.

骨放射性坏死病变的微生物特征:一例与植入物相关感染相关的病例报告。
骨放射性坏死(ORN)病变是头颈癌放疗相关的一种显著的晚期毒性,可能是重要口腔病原体积累的适宜栖息地,这可能增加种植体患者种植体相关感染和康复失败的风险。本临床报告评估了ORN病变、病变附近和对侧种植体的微生物特征,以及在公共癌症研究所接受牙科服务的患者的唾液。患者接受手术清创,但ORN持续存在。这表明ORN病变可能是微生物储存库,构成生物膜相关口腔感染的重要危险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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