Outcomes of the lateral caval flap and conventional techniques for repair of right-sided partial anomalous pulmonary venous connection in adults

William C. Frankel MD , Bogdan A. Kindzelski MD, MS , Benjamin Yang MD , Rashed Mahboubi MD , Miza Salim Hammoud MD , Andrew J. Toth MS , Hani K. Najm MD, MSc , Gösta B. Pettersson MD, PhD , Tara Karamlou MD, MSc
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引用次数: 0

Abstract

Objective

In an effort to overcome limitations of conventional techniques for surgical repair of partial anomalous pulmonary venous connection (PAPVC), we developed the lateral caval flap (LCF) technique, which leverages a native endocardial surface to create unobstructed recruitment of the anomalous pulmonary veins to the left atrium. In this study, we report the long-term outcomes of the LCF and conventional techniques for repair of right-sided PAPVC.

Methods

In total, 109 adult patients (mean age 48 years; 57% male) who underwent right-sided PAPVC repair (53 LCF, 34 single-patch, 13 double-patch, 7 pericardial roll, and 2 Warden procedure) from 1997 to 2022 were retrospectively reviewed. Outcomes included operative mortality, major morbidity, arrythmias, systemic and pulmonary venous pathway obstruction, survival, and reintervention.

Results

Operative mortality was 1% and there were no in-hospital deaths after LCF repair; 4 patients had strokes (4%) including 2 nondisabling strokes after LCF repair (4%), 19 patients developed new postoperative atrial fibrillation/flutter (24%) including 9 after LCF repair (24%), and 27 patients developed new early sinus node dysfunction (26%) including 13 after LCF repair (26%). Although sinus-node dysfunction was transient in most patients, 7 required permanent pacemaker implantation (7%). Survival at 1, 5, 10, and 15 years was 95%, 89%, 86%, and 81%, respectively. At a median follow-up of 6 years, 9 patients developed systemic or pulmonary venous pathway obstruction. Freedom from cardiac reintervention at 5 years was 89% overall and 98% after LCF repair.

Conclusions

All of the described techniques for repair of right-sided PAPVC yielded acceptable short- and long-term outcomes. LCF is a valid technique for right-sided PAPVC repair with a low risk of venous pathway obstruction compared with conventional techniques. Sinus node dysfunction and atrial tachyarrhythmias remain challenges.
外侧腔静脉瓣与常规技术修复成人右侧部分肺静脉连接异常的效果
目的为了克服传统手术修复部分异常肺静脉连接(PAPVC)技术的局限性,我们开发了外侧腔静脉瓣(LCF)技术,该技术利用天然心内膜表面使异常肺静脉不受阻碍地恢复到左心房。在这项研究中,我们报告了LCF和传统技术修复右侧PAPVC的长期结果。方法共纳入109例成人患者(平均年龄48岁;本文回顾性回顾了1997年至2022年间接受右侧PAPVC修复(53例LCF, 34例单补片,13例双补片,7例心包卷,2例Warden手术)的患者(57%男性)。结果包括手术死亡率、主要发病率、心律失常、全身和肺静脉通路阻塞、生存率和再干预。结果LCF修复术后手术死亡率为1%,无院内死亡病例;LCF修复后发生卒中4例(4%),其中2例为非致残性卒中(4%);LCF修复后发生新的房颤/扑动19例(24%),其中9例(24%);LCF修复后发生新的早期窦房结功能障碍27例(26%),其中13例(26%)。虽然大多数患者的窦结功能障碍是短暂的,但有7例(7%)需要永久植入起搏器。1年、5年、10年和15年生存率分别为95%、89%、86%和81%。中位随访6年,9例患者出现全身或肺静脉通路阻塞。5年心脏再干预的自由度总体为89%,LCF修复后为98%。结论所述的所有右侧PAPVC修复技术均获得了可接受的短期和长期结果。与传统技术相比,LCF是一种有效的右侧PAPVC修复技术,静脉通路阻塞的风险低。窦结功能障碍和房性心动过速仍然是挑战。
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