{"title":"Impact of acceleration treatment on treatment plan and delivery qualities in tomotherapy for lung cancer.","authors":"Ryosuke Shirata, Tatsuya Inoue, Yugo Ebinuma, Akihiro Yamano, Takayuki Yagihashi, Hironori Nagata, Yumiko Minagawa, Yuki Mukai, Akiko Sato, Motoko Omura","doi":"10.1002/acm2.70049","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Acceleration treatment (AT) is a novel treatment planning parameter introduced in the tomotherapy-dedicated treatment planning system, Precision. This study explores the effects of AT on tomotherapy plans using helical (TomoHelical) and direct (TomoDirect) irradiation techniques.</p><p><strong>Methods: </strong>This study enrolled 20 patients with lung cancer. Initially, 10 TomoHelical and 10 TomoDirect treatment plans were created for each patient, utilizing patient-specific field width and pitch with an AT setting of 0. These original plans were subsequently reoptimized by changing only the AT values to 1, 4, 7, and 10 without changing other calculation parameters to assess the impact of AT on dosimetric and delivery parameters. Additionally, the deliverability of all plans was evaluated through patient-specific quality assurance using gamma analysis.</p><p><strong>Results: </strong>Increasing the AT from 0 to 10 led to a slight increase in maximum doses and a decrease in minimum doses within the target volume, thereby impairing dose homogeneity. Dose conformity to the target also deteriorated. Conversely, target coverage and delivery time improved considerably with higher AT values. Moreover, doses to organs at risk, including the lung, spinal cord, heart, and esophagus, remained clinically acceptable across all plans. Changes in these doses and the gamma pass rate in patient-specific quality assurance were negligible with variations in AT. This trend was consistent across both delivery techniques.</p><p><strong>Conclusion: </strong>AT is a crucial parameter in tomotherapy planning for modulating plan and delivery qualities. Higher AT values can enhance target coverage and delivery time efficiency.</p>","PeriodicalId":14989,"journal":{"name":"Journal of Applied Clinical Medical Physics","volume":" ","pages":"e70049"},"PeriodicalIF":2.0000,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Applied Clinical Medical Physics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/acm2.70049","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Acceleration treatment (AT) is a novel treatment planning parameter introduced in the tomotherapy-dedicated treatment planning system, Precision. This study explores the effects of AT on tomotherapy plans using helical (TomoHelical) and direct (TomoDirect) irradiation techniques.
Methods: This study enrolled 20 patients with lung cancer. Initially, 10 TomoHelical and 10 TomoDirect treatment plans were created for each patient, utilizing patient-specific field width and pitch with an AT setting of 0. These original plans were subsequently reoptimized by changing only the AT values to 1, 4, 7, and 10 without changing other calculation parameters to assess the impact of AT on dosimetric and delivery parameters. Additionally, the deliverability of all plans was evaluated through patient-specific quality assurance using gamma analysis.
Results: Increasing the AT from 0 to 10 led to a slight increase in maximum doses and a decrease in minimum doses within the target volume, thereby impairing dose homogeneity. Dose conformity to the target also deteriorated. Conversely, target coverage and delivery time improved considerably with higher AT values. Moreover, doses to organs at risk, including the lung, spinal cord, heart, and esophagus, remained clinically acceptable across all plans. Changes in these doses and the gamma pass rate in patient-specific quality assurance were negligible with variations in AT. This trend was consistent across both delivery techniques.
Conclusion: AT is a crucial parameter in tomotherapy planning for modulating plan and delivery qualities. Higher AT values can enhance target coverage and delivery time efficiency.
期刊介绍：
Journal of Applied Clinical Medical Physics is an international Open Access publication dedicated to clinical medical physics. JACMP welcomes original contributions dealing with all aspects of medical physics from scientists working in the clinical medical physics around the world. JACMP accepts only online submission.
JACMP will publish:
-Original Contributions: Peer-reviewed, investigations that represent new and significant contributions to the field. Recommended word count: up to 7500.
-Review Articles: Reviews of major areas or sub-areas in the field of clinical medical physics. These articles may be of any length and are peer reviewed.
-Technical Notes: These should be no longer than 3000 words, including key references.
-Letters to the Editor: Comments on papers published in JACMP or on any other matters of interest to clinical medical physics. These should not be more than 1250 (including the literature) and their publication is only based on the decision of the editor, who occasionally asks experts on the merit of the contents.
-Book Reviews: The editorial office solicits Book Reviews.
-Announcements of Forthcoming Meetings: The Editor may provide notice of forthcoming meetings, course offerings, and other events relevant to clinical medical physics.
-Parallel Opposed Editorial: We welcome topics relevant to clinical practice and medical physics profession. The contents can be controversial debate or opposed aspects of an issue. One author argues for the position and the other against. Each side of the debate contains an opening statement up to 800 words, followed by a rebuttal up to 500 words. Readers interested in participating in this series should contact the moderator with a proposed title and a short description of the topic
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