Rejane Caetani, Susana L Wiechmann, Jacques D Brancher, Vitor H F Oliveira, Rafael Deminice
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引用次数: 0
Abstract
Background: The success of HIV treatment hinges on consistent adherence to antiretroviral therapy (ART).
Objectives: To conduct a longitudinal pilot study to assess the feasibility, acceptability and effectiveness of a mobile app to improve ART adherence.
Method: This study included adults living with HIV and using ART, who were allocated into two groups according to their willingness to use the app: users of the mobile application for ART management (Mobile) and non-users (Control). The application was developed by the researchers, and uses an alarm system to record ART use. Adherence was also assessed using the 'Cuestionario para la Evaluación de la Adhesión al Tratamiento Antiretroviral' (CEAT-VIH) and the Multi-Method Tool questionnaire. Another questionnaire was administered to application users to assess acceptability. After 90 days, all the questionnaires were reapplied.
Results: A significant difference in adherence was observed between the Mobile and Control groups (P = 0.04), but there was no significant difference in time (P = 0.2) or interaction (P = 0.5).
Conclusion: The application was not effective in improving ART adherence and showed low viability, but was considered acceptable among the participants.
背景:艾滋病毒治疗的成功取决于持续坚持抗逆转录病毒治疗(ART)。目的:开展一项纵向试点研究,以评估移动应用程序提高ART依从性的可行性、可接受性和有效性。方法:本研究纳入了使用抗逆转录病毒治疗的艾滋病毒感染者,根据他们使用应用程序的意愿分为两组:使用抗逆转录病毒治疗管理移动应用程序的用户(mobile)和非用户(Control)。该应用程序是由研究人员开发的,并使用报警系统来记录ART的使用情况。还使用“Evaluación de la Adhesión al Tratamiento抗逆转录病毒问卷”(CEAT-VIH)和多方法工具问卷对依从性进行评估。对应用程序用户进行另一份问卷调查,以评估可接受性。90天后重新填写问卷。结果:Mobile组与Control组依从性差异有统计学意义(P = 0.04),但时间差异无统计学意义(P = 0.2),相互作用差异无统计学意义(P = 0.5)。结论:该应用不能有效提高ART依从性,生存力较低,但在参与者中被认为是可接受的。