PEDIATRIC CHOLELITHIASIS AND FACTORS ASSOCIATED WITH CHOLECYSTECTOMY.

Q2 Medicine
Arquivos de Gastroenterologia Pub Date : 2025-02-17 eCollection Date: 2025-01-01 DOI:10.1590/S0004-2803.24612024-048
Karyne Sumico de Lima Uyeno Jordão, Matheus Guedes da Silva, Gabriel Hessel, Roberto Massao Yamada, Joaquim Murray Bustorff-Silva, Maria Ângela Bellomo-Brandão
{"title":"PEDIATRIC CHOLELITHIASIS AND FACTORS ASSOCIATED WITH CHOLECYSTECTOMY.","authors":"Karyne Sumico de Lima Uyeno Jordão, Matheus Guedes da Silva, Gabriel Hessel, Roberto Massao Yamada, Joaquim Murray Bustorff-Silva, Maria Ângela Bellomo-Brandão","doi":"10.1590/S0004-2803.24612024-048","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Cholelithiasis, characterized by hardened deposits in the gallbladder, presents symptoms such as abdominal pain, jaundice, nausea, and potential complications like cholecystitis and choledocholithiasis. Despite increasing diagnoses, literature on pediatric cholelithiasis is limited, with undefined protocols.</p><p><strong>Objective: </strong>This study aims to evaluate the clinical, laboratory characteristics, and outcomes of pediatric cholelithiasis cases, identifying factors associated with cholecystectomy.</p><p><strong>Methods: </strong>A retrospective case series study was conducted on patients treated at a tertiary service, diagnosed with cholelithiasis via ultrasound from 2007 to 2021. Clinical profiles, comorbidities, examinations, procedures, and patient evolution were assessed. Patients were categorized into two groups: Group NC (no cholecystectomy) and Group C (cholecystectomy).</p><p><strong>Results: </strong>Thirty-five patients were included, with 51% females and 60% having comorbidities with abdominal pain was the predominant symptom. Thirty-three patients were managed outpatient while two patients continued follow-up at another facility. Twelve opted for expectant management (Group NC), while 21 underwent cholecystectomy (Group C). Elective laparoscopic cholecystectomy was performed in Group C, with a median age of 11 years and 3 months. Group C showed a higher frequency of abdominal pain compared to Group NC, and this difference was significant (P=0.04). No differences were observed in gender, comorbidities, jaundice, fever, laboratory findings, symptom duration, follow-up time, or age at diagnosis. The median follow-up duration in Group NC was 1 year and 7 months.</p><p><strong>Conclusion: </strong>Abdominal pain was the predominant symptom in patients undergoing cholecystectomy, while comorbidities and laboratory abnormalities showed no significant associations. Although surgical intervention is typically recommended, expectant management proved viable in select cases without ensuing complications during the evaluation period.</p>","PeriodicalId":35671,"journal":{"name":"Arquivos de Gastroenterologia","volume":"62 ","pages":"e24048"},"PeriodicalIF":0.0000,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Arquivos de Gastroenterologia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1590/S0004-2803.24612024-048","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Cholelithiasis, characterized by hardened deposits in the gallbladder, presents symptoms such as abdominal pain, jaundice, nausea, and potential complications like cholecystitis and choledocholithiasis. Despite increasing diagnoses, literature on pediatric cholelithiasis is limited, with undefined protocols.

Objective: This study aims to evaluate the clinical, laboratory characteristics, and outcomes of pediatric cholelithiasis cases, identifying factors associated with cholecystectomy.

Methods: A retrospective case series study was conducted on patients treated at a tertiary service, diagnosed with cholelithiasis via ultrasound from 2007 to 2021. Clinical profiles, comorbidities, examinations, procedures, and patient evolution were assessed. Patients were categorized into two groups: Group NC (no cholecystectomy) and Group C (cholecystectomy).

Results: Thirty-five patients were included, with 51% females and 60% having comorbidities with abdominal pain was the predominant symptom. Thirty-three patients were managed outpatient while two patients continued follow-up at another facility. Twelve opted for expectant management (Group NC), while 21 underwent cholecystectomy (Group C). Elective laparoscopic cholecystectomy was performed in Group C, with a median age of 11 years and 3 months. Group C showed a higher frequency of abdominal pain compared to Group NC, and this difference was significant (P=0.04). No differences were observed in gender, comorbidities, jaundice, fever, laboratory findings, symptom duration, follow-up time, or age at diagnosis. The median follow-up duration in Group NC was 1 year and 7 months.

Conclusion: Abdominal pain was the predominant symptom in patients undergoing cholecystectomy, while comorbidities and laboratory abnormalities showed no significant associations. Although surgical intervention is typically recommended, expectant management proved viable in select cases without ensuing complications during the evaluation period.

小儿胆石症及胆囊切除术相关因素。
背景:胆石症以胆囊硬化沉积为特征,表现为腹痛、黄疸、恶心等症状,以及胆囊炎和胆总管结石等潜在并发症。尽管越来越多的诊断,关于儿童胆石症的文献是有限的,没有明确的方案。目的:本研究旨在评估儿童胆石症病例的临床、实验室特征和预后,确定胆囊切除术的相关因素。方法:对2007年至2021年在三级医院接受超声诊断为胆石症的患者进行回顾性病例系列研究。评估临床概况、合并症、检查、程序和患者进展。患者分为两组:NC组(未切除胆囊)和C组(切除胆囊)。结果:纳入35例患者,51%为女性,60%有合并症,腹痛为主要症状。33例患者接受门诊治疗,2例患者在另一家机构继续随访。选择保守治疗12例(NC组),胆囊切除术21例(C组)。C组择期行腹腔镜胆囊切除术,中位年龄11岁3个月。C组腹痛发生率高于NC组,差异有统计学意义(P=0.04)。在性别、合并症、黄疸、发热、实验室结果、症状持续时间、随访时间或诊断年龄方面没有观察到差异。NC组的中位随访时间为1年7个月。结论:腹痛是胆囊切除术患者的主要症状,而合并症与实验室检查无显著相关性。虽然手术干预通常被推荐,但在评估期间,在没有并发症的情况下,预期治疗被证明是可行的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Arquivos de Gastroenterologia
Arquivos de Gastroenterologia Medicine-Gastroenterology
CiteScore
2.00
自引率
0.00%
发文量
109
审稿时长
9 weeks
期刊介绍: The journal Arquivos de Gastroenterologia (Archives of Gastroenterology), a quarterly journal, is the Official Publication of the Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia IBEPEGE (Brazilian Institute for Studies and Research in Gastroenterology), Colégio Brasileiro de Cirurgia Digestiva - CBCD (Brazilian College of Digestive Surgery) and of the Sociedade Brasileira de Motilidade Digestiva - SBMD (Brazilian Digestive Motility Society). It is dedicated to the publishing of scientific papers by national and foreign researchers who are in agreement with the aim of the journal as well as with its editorial policies.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信