Clinical outcomes and hospital-reported cost associated with surgical site infections and the co-occurrence of hospital-onset bacteremia and fungemia across US hospitals.

IF 3 4区 医学 Q2 INFECTIOUS DISEASES
ChinEn Ai, Molly Jung, Samantha Bastow, Ghislene Adjaoute, David Bostick, Kalvin C Yu
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引用次数: 0

Abstract

Objective: To evaluate the hospital-reported cost of care, clinical burden, and incidence of hospital-onset bacteremia and fungemia (HOB) for hospital admissions with surgical site infections (SSI).

Methods: A cross-sectional study of 38 acute-care hospital admissions with a procedure under the National Healthcare Safety Network (NHSN) surveillance for SSI was conducted. SSI admissions were identified through NHSN reporting by the hospital. Clinical outcomes were estimated for SSI compared to no SSI controls using propensity matching and multivariable adjusted models that controlled for patient and hospital demographics; these endpoints were also compared for SSI admissions with and without HOB co-occurrence.

Results: The rate of hospital-reported SSI was 0.15 per 100 admissions with a procedure under surveillance for SSI. Admissions with SSI compared to no SSI had significantly higher incremental hospital-reported cost of $30,689 and length of stay (LOS) was 11.6 days higher. The incidence of HOB was 6-fold higher in admissions with SSI compared to no SSI. For SSI admissions with HOB vs. no HOB, HOB added $28,049 to cost of care and 6.5 days to the LOS.

Conclusions: Hospital-reported SSIs were associated with higher clinical and economic burden. Patients with SSI and HOB had even more deleterious outcomes. These data may inform programs to augment infection prevention bundles targeting SSIs and downstream complications or comorbidities like HOB.

临床结果和医院报告的费用与手术部位感染以及在美国各医院内同时发生的院内始发菌血症和真菌血症相关
目的:评估医院报告的手术部位感染(SSI)住院患者的护理费用、临床负担和院源性菌血症和真菌血症(HOB)的发生率。方法:采用国家医疗安全网络(NHSN)监测程序对38例急诊住院患者进行横断面研究。SSI入院是通过医院的NHSN报告确定的。使用倾向匹配和控制患者和医院人口统计数据的多变量调整模型,估计SSI患者与无SSI对照组的临床结果;这些终点还比较了合并和不合并HOB的SSI入院情况。结果:医院报告的SSI率为0.15 / 100例住院患者,并对SSI进行了监控。与未接受SSI的患者相比,接受SSI的患者住院报告费用增加了30,689美元,住院时间(LOS)增加了11.6天。有SSI的住院患者的HOB发生率比无SSI的住院患者高6倍。对于有HOB和没有HOB的SSI入院,HOB增加了28,049美元的护理费用和6.5天的LOS。结论:医院报告的ssi与较高的临床和经济负担相关。SSI和HOB患者有更有害的结果。这些数据可以为增加针对ssi和下游并发症或合并症(如HOB)的感染预防包的计划提供信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.40
自引率
6.70%
发文量
289
审稿时长
3-8 weeks
期刊介绍: Infection Control and Hospital Epidemiology provides original, peer-reviewed scientific articles for anyone involved with an infection control or epidemiology program in a hospital or healthcare facility. Written by infection control practitioners and epidemiologists and guided by an editorial board composed of the nation''s leaders in the field, ICHE provides a critical forum for this vital information.
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