The importance of source control in the treatment of infections in elderly patients aged 80 and above

Tatsuro Sakai , Youichi Yanagawa , Hiroshi Ito
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Abstract

Background

There is currently no research in super-elderly patients with source of infections that require invasive treatment

Objectives

We retrospectively examined the impact on outcomes of performing or not performing such procedures in super-elderly patients with infection sources

Methods

The subjects were patients aged 80 years or older who were transported by ambulance to Numazu City Hospital and diagnosed with "infections requiring source control" in the emergency department during the six-year period. Infections requiring source control were generally defined as infections for which procedures such as drainage, debridement, or surgical resection to physically reduce the bacterial load at the source were necessary

Results

There were 201 patients were enrolled. The average age was 87.0 years. There were 175 cases where procedures were performed, and 24 cases (11.9 %) resulted in death. Hepatobiliary diseases were the most common, accounting for 153 cases, followed by renal infections with 25 cases. Compared to the surviving group, the fatal group had a statistically significantly lower rate of source control, shorter hospital stays, and higher Sequential Organ Failure Assessment and Acute Physiology and Chronic Health Evaluation II scores. Among them, only source control was identified as an independent factor related to survival by multivariate analysis

Conclusion

This study suggests that performing source control in patients, even those aged 80 years and older, might increase survival rates
源头控制在80岁及以上老年患者感染治疗中的重要性
背景:目前还没有针对感染源需要侵入性治疗的超高龄患者的研究。目的:我们回顾性研究了对感染源需要侵入性治疗的超高龄患者进行或不进行侵入性治疗对结果的影响。方法:研究对象是在6年内由救护车运送到Numazu市医院并在急诊科诊断为“需要源性控制的感染”的80岁及以上患者时期。需要源头控制的感染通常定义为需要采取引流、清创或手术切除等措施来物理减少源头细菌负荷的感染。结果共纳入201例患者。平均年龄为87.0岁。175例进行了手术,24例(11.9%)导致死亡。最常见的是肝胆疾病,153例,其次是肾脏感染,25例。与存活组相比,死亡组的源控制率具有统计学意义上的显著降低,住院时间更短,序期器官衰竭评估和急性生理和慢性健康评估II评分更高。结论本研究提示,对80岁及以上的患者进行源控制,可能会提高患者的生存率
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来源期刊
JEM reports
JEM reports Emergency Medicine
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